Carcinoma ex pleomorphic adenoma of the trachea: A case report

被引:2
作者
Heng-Xing Gao [1 ]
Quan Li [2 ]
Wen-Li Chang [3 ]
Ya-Long Zhang [3 ]
Xiao-Zhi Wang [1 ]
Xue-Xue Zou [2 ]
机构
[1] Respiratory Department, Binzhou Medical University Hospital
[2] Department of Radiology, Binzhou Medical University Hospital
[3] Department of Pathology, Binzhou Medical University Hospital
关键词
Case report; Carcinoma ex pleomorphic adenoma; Trachea; Pleomorphic adenoma;
D O I
暂无
中图分类号
R734.1 [气管、支气管肿瘤];
学科分类号
100214 ;
摘要
BACKGROUND Carcinoma ex pleomorphic adenoma(CXPA) is defined as a malignant salivary gland tumor arising from a primary or recurrent pleomorphic adenoma. Only three cases of CXPA of the trachea have been reported in the literature.CASE SUMMARY We report a case of tracheal CXPA in a 55-year-old woman, who presented with a more than 3-mo history of progressive dyspnea. Computed tomography of the neck and thorax revealed an inhomogeneous, broad-based lesion arising from the tracheal wall on the right side. Endoscopy revealed a subglottic neoplasm causing up to 90% luminal stenosis. The tumor was resected using a highfrequency electrosurgical snare combined with argon plasma coagulation.Histopathology and immunohistochemistry revealed that the tumor was a CXPA of the trachea.CONCLUSION We report the fourth case of tracheal CXPA, and present the first instance of resection of CXPA using high-frequency electrosurgical snare and laser ablation.We also discuss the pathogenesis, diagnosis, histopathology, and systemic therapy of this rare disease.
引用
收藏
页码:2623 / 2629
页数:7
相关论文
共 18 条
[1]  
Carcinoma ex pleomorphic adenoma,with particular emphasis on early lesions. Di Palma S. Head Neck Pathol . 2013
[2]  
Pleomorphic adenoma with an endobronchial resection. Matsubara M,Yasuo M,Tanabe T,Tsushima K,Urushihata K,Yamamoto H,Hanaoka M,Koizumi T,Fujimoto K,Kubo K,Yamazaki Y,Uehara T. Journal of Internal Medicine . 2008
[3]  
Noninvasive carcinoma ex pleomorphic adenoma of the parotid gland:A difficult diagnosis on fine needle aspiration. Scognamiglio T,Joshi R,Kuhel WI,Tabbara SO,Rezaei MK,Hoda RS. Cytojournal . 2015
[4]  
Primary carcinoma ex pleomorphic adenoma of the bronchus:Report of two cases and review of the literature. Xu J,Wan J,Zhang M. Int J Clin Exp Med . 2017
[5]  
Carcinoma ex pleomorphic adenoma:case report and options for systemic therapy. Chooback N,Shen Y,Jones M,Kasaian K,Martin M,Ng T,Thomson T,Marra M,Laskin J,Ho C. Curr Oncol . 2017
[6]   Endoscopic surgery with a flexible bronchoscope and argon plasma coagulation for tracheobronchial tumors [J].
Okada, S ;
Yamauchi, H ;
Ishimori, S ;
Satoh, S ;
Sugawara, H ;
Tanaba, Y .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2001, 121 (01) :180-182
[7]  
Carcinoma ex pleomorphic adenoma: Pathologic analysis of 73 cases[J] . Jean E Lewis,Kerry D Olsen,Thomas J Sebo. &nbspHuman Pathology . 2001 (6)
[8]  
Carcinoma ex Pleomorphic Adenoma: A Comprehensive Review of Clinical, Pathological and Molecular Data[J] . Joyce Antony,Vinod Gopalan,Robert Smith,Alfred Lam. &nbspHead and Neck Pathology . 2012 (1)
[9]  
Prognostic factors affecting the clinical outcome of carcinoma ex pleomorphic adenoma in the major salivary gland. Zhao J,Wang J,Yu C,et al. World J Surg Oncol . 2013
[10]  
Malignant pleomorphic adenoma (malignant mixed tumor)of the trachea:a case report and review of the literature. DEMIRA F,TOP?U S,KURUL C,et al. European Archives of Oto Rhino Laryngology . 2003