Did splenectomy influence relapse of chronic myelogenous leukemia after allogeneic hematopoietic stem cell transplantation?
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作者:
WANG Jun
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Department of Hematology and Oncology,Zhongda Hospital,Southeast UniversityDepartment of Hematology and Oncology,Zhongda Hospital,Southeast University
WANG Jun
[1
]
DING Jia-hua
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Department of Hematology and Oncology,Zhongda Hospital,Southeast UniversityDepartment of Hematology and Oncology,Zhongda Hospital,Southeast University
DING Jia-hua
[1
]
CHEN Bao-an
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Department of Hematology and Oncology,Zhongda Hospital,Southeast UniversityDepartment of Hematology and Oncology,Zhongda Hospital,Southeast University
CHEN Bao-an
[1
]
BAO Wen
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Department of Hematology and Oncology,Zhongda Hospital,Southeast UniversityDepartment of Hematology and Oncology,Zhongda Hospital,Southeast University
BAO Wen
[1
]
YU Zheng-ping
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Department of Hematology and Oncology,Zhongda Hospital,Southeast UniversityDepartment of Hematology and Oncology,Zhongda Hospital,Southeast University
YU Zheng-ping
[1
]
MA Jin-long
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Department of Hematology and Oncology,Zhongda Hospital,Southeast UniversityDepartment of Hematology and Oncology,Zhongda Hospital,Southeast University
MA Jin-long
[1
]
机构:
[1] Department of Hematology and Oncology,Zhongda Hospital,Southeast University
To the editor:Up to now there was no case reported on whether splenectomy influenced relapse of chronic myelogenous leukemia(CML)after allogeneic hematopoietic stem cell transplantation(allo-HSCT).Here we report a relapsed CML patient after allo-HSCT and splenectomy.This patient is a 52-year-old man who initially presented with CML in chronic phase in 2002.At diagnosis he underwent alloHSCT from his HLA-identical brother.The conditioning regimen was the busulfan and cyclophosphamide(BU-CY2)and then he received cyclosporine and methotrexate for graft-versus-host disease(GVHD)prophylaxis.Because of pancytopenia,the patient received splenectomy and then had a rapid hematopoeitic recovery without