Total saponins of Panax notoginseng protected rabbit iliac artery against balloon endothelial denudation injury

被引:0
作者
Si-wei CHEN
机构
关键词
<Keyword>Panax ginseng; saponins; balloon dilatation; restenosis; extracellular matrix; vascular smooth muscle;
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中图分类号
R285 [中药药理学];
学科分类号
1008 ;
摘要
AIM: To investigate whether total Panax notoginseng saponins (PNS) could protect endothelium of rabbit iliac artery against balloon endothelial denudation (BED) injury. METHODS: The morphology changes of the endothelium were observed with scanning electron microscope (SEM) and hematoxylin and eosin stain after BED of rabbit iliac artery at 0,4,6, and 8 week respectively. Vascular endothelial growth factor (VEGF) and matrix
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页码:49 / 54
页数:6
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  • [1] Detection of coronary restenosis by exercise electrocardiography thallium-201 perfusion imaging and coronary angiography in asymptomatic patients after percutaneous transluminal coronary angioplasty. Beygui F,Feuvre CL,Maunoury C,Helft G,Antonietti T,Metzger JP,et al. The American Journal of Cardiology . 2000
  • [2] Matrix metalloproteinase-2 is elevated in the plasma of women with preeclampsia. Narumiya H,Zhang Y,Fernandez-Patron C,Guilbert LJ,Davidge ST. Hypertension in Pregnancy . 2001
  • [3] Improving of percutaneous coronary intervention. Nash IS. American Heart Journal . 1999
  • [4] Angiogenesis in renal cell carcinoma: Evaluation of microvessel density, vascular endothelial growth factor and matrix metal-lopro-teinases. Zhang XH,Yamashita M,Uetsuki H,Kakehi Y. International Journal of Urology . 2002
  • [5] The extracellular matrix can regulate vascular cell migration, proliferation, and survival: relationships to vascular disease. Raines,Elaine W. International Journal of Experimental Pathology . 2000
  • [6] Improvement of early postburn cardiac function by use of Panax notoginseng and immediate total eschar excision in one operation. Huang YS,Yang ZC,Yan BG,Hu XC,Li AN,Crowther RS. Burns . 1999
  • [7] Cyclosporine A up-regulates expression of matrix metalloproteinase 2 and vascular endothelial growth factor in rat heart. Rossella B,Luigi R,Rita R. International Journal of Immunopharmacology . 2003
  • [8] Fibroblast response to hypoxia: the relationship between angiogenesis and matrix regulation. Steinbrech DS,Longaker MT,Mehrara BJ,Saadeh PB,Chin GS,Gerrets RP,et al. Journal of Surgical Research . 1999
  • [9] Effect of BO-653 and probucol on c-MYC and PDGF-A messenger RNA of the iliac artery after balloon denudation in cholesterol-fed rabbits. Inoue K,Cynshi O,Kawabe Y,Nakamura M,Miyauchi K,Kimura T,et al. Atherosclerosis . 2002
  • [10] Isolation of a small chitinase-like antifungal protein from Panax notoginseng (sanchi ginseng) roots. Lam SK,Ng TB. International Journal of Biochemistry Cell Biology The . 2001