Thiamine hydrochloride(VB1):An efficient catalyst for one-pot synthesis of α-aminophosphonates under ultrasonic irradiation

被引:0
|
作者
Priyanka G.Mandhane [1 ]
Ratnadeep S.Joshi [1 ]
Deepak R.Nagargoje [1 ]
Charansingh H.Gill [1 ]
机构
[1] Department of Chemistry,Dr.Babasaheb Ambedkar Marathwada University,Aurangabad,Maharashtra 431004,India
关键词
Thiamine hydrochloride(VB1); α-Aminophosphonates; Triethyl phosphate; Water; Ultrasonication; Green synthesis;
D O I
暂无
中图分类号
O621.3 [有机合成化学];
学科分类号
摘要
An efficient synthesis of novelα-aminophosphonates by the reaction of aldehydes and amines with triethyl phosphite in the presence of the easily available,inexpensive,and nontoxic catalyst thiamine hydrochloride(VB1).This method affords theα-aminopho-sphonates under the influence of ultrasound irradiation in aqueous medium,in short reaction times(4-6 min),high yields(85-95%), with improved purity.The process is green,mild,inexpensive and excellent yields are the main compensation of this procedure.
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页码:563 / 566
页数:4
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