Research on the Extraction of Flavonoids from Ginseng Root and its Ability in Antioxidant

被引:0
|
作者
Ru ZHANG
Bianling ZHANG
Zhiyong LUO
机构
[1] Molecular Biology Research Center,School of Life Sciences,Central South University
[2] College of Chemistry and Chemical Engineering,Hunan Institute of Engineering
基金
中国国家自然科学基金;
关键词
Ginseng root flavonoids; Extraction; Antioxidant; Rat; Activity of SOD;
D O I
暂无
中图分类号
R285 [中药药理学];
学科分类号
1008 ;
摘要
[Objective]The flavonoids were extracted from ginseng root and its antioxidant activity was studied.[Method]The method of ethanol reflow and polyamide enrichment were adopted in the extract of the flavonoids from ginseng root.The antioxidant of the flavonoids from ginseng root was tested with DPPH method,Fenton method and rats feeding.[Results]When the concentration of the ginseng root flavonoids was over 0.5 mg/mL,the scavenging rate of the DPPH free radical was more than 80%and 0.6 mg/mL,the hydroxyl free radical,as high as70.8%.The activity of SOD in rat brain could increase over 17.97%after the rat was fed with the flavonoids at the concentration of 80-120mg/kg per day for five weeks.[Conclusion]The ginseng root flavonoids had a strong scavenging effect on DPPH free radical and hydroxyl free radical in vitro and also an intensifying effect on the activity of SOD in SD rat brain in vivo.
引用
收藏
页码:34 / 37
页数:4
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