Metabolomics and Its Potential in Drug Discovery and Development From TCM

被引：4
作者：
Hang Chu [1 ]
Ai-Hua Zhang [1 ]
Ying Han [1 ]
Xi-Jun Wang [1 ]
机构：
[1] National TCM Key Lab of Serum Pharmacochemistry, Key Laboratory of Metabolomics and Chinmedomics, Department of Pharmaceutical Analysis,Heilongjiang University of Chinese Medicine
来源：
World Journal of Traditional Chinese Medicine | 2015年 / 1卷 / 04期
基金：
黑龙江省自然科学基金;
关键词：
Metabolomics; traditional Chinese medicine; formulae; biomarker; drug discovery;
D O I：
暂无
中图分类号：
R28 [中药学];
学科分类号：
1008 ;
摘要：
Metabolomics, an omic science in systems biology, is the comprehensive profiling of metabolic changes occurring in living systems and has been widely used in the modern research of traditional Chinese medicine(TCM). TCM is a complex medical science, which reflects rich philosophical dialectical thought, puts the human body into a large system for observation and keeps human in a healthy status. For TCM aroused great interest in the whole world, herbs and Chinese medical formulae(CMF) as treatment methods have also been widely attention.Metabolomics represents a powerful way that provides a dynamic drawing of the phenotype of biological systems via the research of endogenous metabolites, and its methods are similar to those of TCM. This review summarizes the advantages of metabolomics, highlight the key role of biomarkers for drug discovery and development of TCM.
引用
收藏
页码：26 / 32
页数：7
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