The impact toughness of TC21 alloy after different types of forging and heat treatments was studied. The results show that heat treatment at 915 ℃ for 1 h followed by air-cooling can achieve the highest impact toughness. The crack propagation path of bimodal microstructure is different from that of lamellar microstructure. Boundaries of primary α grain are observed to be preferential sites for microcrack nucleation. With the increase of heat treatment temperature,the volume fraction of primary α phase decreases and the nucleation sites of microcrack at the primary α phase boundaries also decrease,the impact toughness value is effectively improved. The microcracks of lamellar microstructure are located on α/β interface,or the boundary of colony,and/or grain boundary α phase. The crack propagates cross the colony,or along the colony boundary,and/or along β grain boundary. The crack propagation path of lamellar microstructure is dependent on the size,direction of colony. The crack path deflects at grain boundaries,colony boundaries,or arrests and deviates at α/β interface because of crisscross α lamellar. Therefore the impact toughness value of basket microstructure is higher than that of Widmanstatten microstructure.