Characteristics of PVT1 and Its Roles in Diseases

被引：4
作者：
Li Wang [1 ]
Jin-hua He [1 ]
Ze-ping Han [1 ]
机构：
[1] Department of Laboratory, Panyu Central Hospital
来源：
ChineseMedicalSciencesJournal | 2014年 / 29卷 / 04期
关键词：
long non-coding RNAs; plasmacytoma variant translocation 1 gene; expression; characteristics;
D O I：
暂无
中图分类号：
R363 [病理生理学];
学科分类号：
100104 ;
摘要：
With the development of genome-wide sequencing technology, 195 types of functional, long non-coding RNAs(lnc RNAs) have been identified so far, and their cellular roles are gradually being revealed. Lnc RNAs have now become a hotspot in the field of life sciences. These small molecules exist in almost all higher eukaryotes and play very important regulatory roles in these organisms. This review briefly summarizes the recent progress in research on plasmacytoma variant translocation 1 gene(PVT1), an lnc RNA.
引用
收藏
页码：236 / 238
页数：3
相关论文
共 50 条
  • [31] Promoter of IncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
    Cho, Seung Woo
    Xu, Jin
    Sun, Ruping
    Mumbach, Maxwell R.
    Carter, Ave C.
    Chen, Y. Grace
    Yost, Kathryn E.
    Kim, Jeewon
    He, Jing
    Nevins, Stephanie A.
    Chin, Suet-Feung
    Caldas, Carlos
    Liu, S. John
    Horlbec, Max A.
    Lim, Daniel A.
    Weissman, Jonathan S.
    Curtis, Christina
    Chang, Howard Y.
    CELL, 2018, 173 (06) : 1398 - +
  • [32] Downregulation of lncRNA PVT1 inhibits proliferation and migration of mesothelioma cells by targeting FOXM1
    Fujii, Yutaro
    Amatya, Vishwa Jeet
    Kushitani, Kei
    Suzuki, Rui
    Kai, Yuichiro
    Kambara, Takahiro
    Takeshima, Yukio
    ONCOLOGY REPORTS, 2022, 47 (02)
  • [33] Downregulation of long noncoding RNA PVT1 attenuates paclitaxel resistance in glioma cells
    Song, Tiejun
    Yan, Lei
    Cai, Kerui
    Zhao, Tianshu
    Xu, Meiling
    CANCER BIOMARKERS, 2018, 23 (03) : 447 - 453
  • [34] Long noncoding RNA PVT1: potential oncogene in the development of acute lymphoblastic leukemia
    Yazdi, Narjes
    Houshmand, Mohammad
    Atashi, Amir
    Kazemi, Alireza
    Najmedini, Ali Anjam
    Zarif, Mahin Nikougoftar
    TURKISH JOURNAL OF BIOLOGY, 2018, 42 (05) : 405 - 413
  • [35] PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance
    Tabury, Kevin
    Monavarian, Mehri
    Listik, Eduardo
    Shelton, Abigail K.
    Choi, Alex Seok
    Quintens, Roel
    Arend, Rebecca C.
    Hempel, Nadine
    Miller, C. Ryan
    Gyorrfy, Balazs
    Mythreye, Karthikeyan
    LIFE SCIENCE ALLIANCE, 2022, 5 (11)
  • [36] lncRNA PVT1 and its splicing variant function as competing endogenous RNA to regulate clear cell renal cell carcinoma progression
    Yang, Tao
    Zhou, Hui
    Liu, Peijun
    Yan, Libin
    Yao, Weimin
    Chen, Ke
    Zeng, Jin
    Li, Heng
    Hu, Junhui
    Xu, Hua
    Ye, Zhangqun
    ONCOTARGET, 2017, 8 (49) : 85353 - 85367
  • [37] Amplification of lncRNA PVT1 promotes ovarian cancer proliferation by binding to miR-140
    Ding, Yuqin
    Fang, Qianjin
    Li, Yan
    Wang, Yanni
    MAMMALIAN GENOME, 2019, 30 (7-8) : 217 - 225
  • [38] LncRNA PVT1 is a novel mediator promoting the angiogenesis response associated with collateral artery formation
    Li, You
    Xue, Jing-Yi
    Chen, Shuang
    Wang, Chao
    Sun, Ping
    Fu, Shuai
    Li, Yitong
    Zhao, Peng
    Tian, Jiawei
    Du, Guo-Qing
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2022, 151
  • [39] Investigation of LncRNA PVT1 and MiR-21-5p Expression as Promising Novel Biomarkers for Autism Spectrum Disorder
    Jiang, Mingjun
    Chen, Guanwen
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2023, 73 (9-10) : 865 - 873
  • [40] Amplification and the clinical significance of circulating cell-free DNA of PVT1 in breast cancer
    Li, Xujing
    Chen, Weijuan
    Wang, Hui
    Wei, Qun
    Ding, Xiaodi
    Li, Wentong
    ONCOLOGY REPORTS, 2017, 38 (01) : 465 - 471
12345