[Objective] To establish a reasonable extraction technology for total flavonoids from Vitex quinata,and to provide theoretical basis for the development and utilization of V. quinata. [Methods]Ethanol concentration,ethanol dosage,extracting times and extracting time were taken as the investigation factors. Extraction technology was optimized by orthogonal test with the content of total flavonoids in V. quinata as the index. [Results] The optimal extraction technology was as follows: 70% ethanol,1∶ 12( W / V) solid-liquid ratio,three extraction times and1 h for each extraction. [Conclusions]This extraction technology was simple,stable and effective,and was suitable for the extraction of total flavonoids.