Caffeine therapy in preterm infants

被引:22
|
作者
Hesham Abdel-Hady [1 ]
Nehad Nasef [1 ]
Abd Elazeez Shabaan [1 ]
Islam Nour [1 ]
机构
[1] Neonatal Intensive Care Unit,Mansoura University Children’s Hospital
关键词
Apnea; Caffeine; Preterm; Methylxanthines;
D O I
暂无
中图分类号
R722.6 [早产儿疾病];
学科分类号
100202 ;
摘要
Caffeine is the most commonly used medication for treatment of apnea of prematurity. Its effect has been well established in reducing the frequency of apnea, intermittent hypoxemia, and extubation failure in mechanically ventilated preterm infants. Evidence for additional short-term benefits on reducing the incidence of bronchopulmonary dysplasia and patent ductus arteriosus has also been suggested. Controversies existamong various neonatal intensive care units in terms of drug efficacy compared to other methylxanthines, dosage regimen, time of initiation, duration of therapy, drug safety and value of therapeutic drug monitoring. In the current review, we will summarize the available evidence for the best practice in using caffeine therapy in preterm infants.
引用
收藏
页码:81 / 93
页数:13
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