Link between dysregulated hypoxia signaling and aberrant methylation in clear cell renal cell carcinoma?

被引：0
作者：
Niraj Shenoy
机构：
[1] MayoClinic
来源：
Chinese Journal of Cancer Research | 2017年 / 29卷 / 02期
关键词：
RCC; it; HIF; is; gene; in; Link between dysregulated hypoxia signaling and aberrant methylation in clear cell renal cell carcinoma; DNMT; cell;
D O I：
暂无
中图分类号：
R737.11 [肾、肾盂肿瘤];
学科分类号：
100214 ;
摘要：
<正>Dysregulated pseudo-hypoxia(through its effects on cell survival,angiogenesis,metabolism,invasion)and epigenetic dysregulation[through widespread suppression of tumor suppressor genes involved in cell cycle,apoptosis,adhesion immune evasion,etc.(1)]are considered to be the two central driving pathogenic features in the progression of clear cell Renal Cell Carcinoma(cc RCC)(2,3).These two
引用
收藏
页码：166 / 167
页数：2
相关论文
共 2 条
[1]  
Aberrant DNA methyltransferase 1 expression in clear cell renal cell carcinoma development and progression[J]. Ming Li,Ying Wang,Yongsheng Song,Renge Bu,Bo Yin,Xiang Fei,Qizhen Guo,Bin Wu. Chinese Journal of Cancer Research. 2014(04)
[2]  
The Regulation and Interactions of the Hypoxia Inducible Factor Pathway in Carcinogenesis and Potential Cancer Therapeutic Strategies[J] . Niraj Shenoy,Makardhwaj Shrivastava,Vineeth Sukrithan,Dimitra Papaspyridi,Karine Darbinyan. Journal of Cancer Therapy . 2015 (06)
1