In this article, we consider some classes of interpolating spline with difference. derivative and integral interpolating conditions respectively. Let Δ:a=x<u<v≤X≤U<v≤X…X≤U,<v≤xbe a partition of [a, b], where and suppose (x) be a function defined on [a, b] and (x)∈C[a,b]. In the first place, we consider cubic interpolating splines s(x) and s(x) satisfying the following conditions respectively: (i) s(x) (s(x))∈C[a, b]; (ii) s(x) (s(x)) is cubic polynomial in each interval [x, x]; (ⅲ) s(v)-s(u)=(v)