Current status of imaging in nonalcoholic fatty liver disease

被引:1
作者
Qian Li [1 ]
Manish Dhyani [1 ,2 ]
Joseph R Grajo [3 ]
Claude Sirlin [4 ]
Anthony E Samir [1 ]
机构
[1] Department of Radiology, Massachusetts General Hospital, Harvard Medical School
[2] Department of Radiology, Lahey Hospital and Medical Center
[3] Department of Radiology, Division of Abdominal Imaging, University of Florida College of Medicine
[4] Altman Clinical Translational Research Institute,University of California,San Diego
基金
美国国家卫生研究院;
关键词
Simple steatosis; Non-alcoholic fatty liver disease; Ultrasonography; Computed tomography; Nonalcoholic steatohepatitis; Elastography; Magnetic resonance;
D O I
暂无
中图分类号
R575.5 [肝代谢障碍]; R445 [影像诊断学];
学科分类号
1002 ; 100201 ; 100207 ;
摘要
Non-alcoholic fatty liver disease(NAFLD) is the most common diffuse liver disease, with a worldwide prevalence of 20% to 46%. NAFLD can be subdivided into simple steatosis and nonalcoholic steatohepatitis. Most cases of simple steatosis are non-progressive, whereas nonalcoholic steatohepatitis may result in chronic liver injury and progressive fibrosis in a significant minority. Effective risk stratification and management of NAFLD requires evaluation of hepatic parenchymal fat, fibrosis, and inflammation. Liver biopsy remains the current gold standard; however, non-invasive imaging methods are rapidly evolving and may replace biopsy in some circumstances. These methods include well-established techniques, such as conventional ultrasonography, computed tomography, and magnetic resonance imaging and newer imaging technologies, such as ultrasound elastography, quantitative ultrasound techniques, magnetic resonance elastography, and magnetic resonancebased fat quantitation techniques. The aim of this article is to review the current status of imaging methods for NAFLD risk stratification and management, including their diagnostic accuracy, limitations, and practical applicability.
引用
收藏
页码:530 / 542
页数:13
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