Spermatogonial Stem Cell Self-renewal and Differentiation

被引：0
|
作者：
Li-Huan Cao [1 ]
Qiao-Li Zhang [1 ]
Xin-Hua Lin [1 ]
机构：
[1] State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University
来源：
生殖与发育医学（英文） | 2017年 / 1卷 / 03期
关键词：
Differentiation; Self-renewal; Spermatogonial Stem Cells;
D O I：
暂无
中图分类号：
R321.1 [生殖细胞];
学科分类号：
摘要：
Mammalian spermatogenesis is a complicated and precisely controlled process that requires spermatogonial stem cells(SSCs). SSCs maintain the stem cell pool, balance self-renewal–commitment with differentiation, and produce millions of sperm daily. Self-renewal and differentiation are controlled by intrinsic factors within SSCs and extrinsic factors from the "niche." In this review, we discuss the biology of SSCs and the factors regulating their self-renewal and differentiation.
引用
收藏
页码：171 / 178
页数：8
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