Spermatogonial Stem Cell Self-renewal and Differentiation

被引：0
|
作者：
Li-Huan Cao [1 ]
Qiao-Li Zhang [1 ]
Xin-Hua Lin [1 ]
机构：
[1] State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University
来源：
生殖与发育医学（英文） | 2017年 / 1卷 / 03期
关键词：
Differentiation; Self-renewal; Spermatogonial Stem Cells;
D O I：
暂无
中图分类号：
R321.1 [生殖细胞];
学科分类号：
071008 ;
摘要：
Mammalian spermatogenesis is a complicated and precisely controlled process that requires spermatogonial stem cells(SSCs). SSCs maintain the stem cell pool, balance self-renewal–commitment with differentiation, and produce millions of sperm daily. Self-renewal and differentiation are controlled by intrinsic factors within SSCs and extrinsic factors from the "niche." In this review, we discuss the biology of SSCs and the factors regulating their self-renewal and differentiation.
引用
收藏
页码：171 / 178
页数：8
相关论文
共 50 条
  • [21] Regulation of self-renewal and differentiation by the intestinal stem cell niche
    Trevor M. Yeung
    Luis A. Chia
    Cynthia M. Kosinski
    Calvin J. Kuo
    Cellular and Molecular Life Sciences, 2011, 68 : 2513 - 2523
  • [22] Redox homeostasis: the linchpin in stem cell self-renewal and differentiation
    Kui Wang
    Tao Zhang
    Qiang Dong
    Edouard Collins Nice
    Canhua Huang
    Yuquan Wei
    Cell Death & Disease, 2013, 4 : e537 - e537
  • [23] The involvement of bioactive factors in the self-renewal and stemness maintenance of spermatogonial stem cells
    Yang, Guoqing
    He, Yuqing
    Yang, Hao
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2021, 476 (04) : 1813 - 1823
  • [24] The ERGonomics of hematopoietic stem cell self-renewal
    Lacadie, Scott A.
    Zon, Leonard I.
    GENES & DEVELOPMENT, 2011, 25 (04) : 289 - 293
  • [25] Roles of autophagy in controlling stem cell identity: a perspective of self-renewal and differentiation
    Areechun Sotthibundhu
    Wilasinee Promjuntuek
    Min Liu
    Sanbing Shen
    Parinya Noisa
    Cell and Tissue Research, 2018, 374 : 205 - 216
  • [26] Assessing self-renewal and differentiation in human embryonic stem cell lines
    Cai, Jingli
    Chen, Jia
    Liu, Ying
    Miura, Takumi
    Luo, Yongquan
    Loring, Jeanne F.
    Freed, William J.
    Rao, Mahendra S.
    Zeng, Xianmin
    STEM CELLS, 2006, 24 (03) : 516 - 530
  • [27] Origin of Cancer Stem Cells: The Role of Self-Renewal and Differentiation
    Xiong-Zhi Wu
    Annals of Surgical Oncology, 2008, 15 : 407 - 414
  • [28] MicroRNAs are involved in the self-renewal and differentiation of cancer stem cells
    Wang, Zheng-ming
    Du, Wen-jun
    Piazza, Gary A.
    Xi, Yaguang
    ACTA PHARMACOLOGICA SINICA, 2013, 34 (11) : 1374 - 1380
  • [29] Empowering self-renewal and differentiation: the role of mitochondria in stem cells
    Jalees Rehman
    Journal of Molecular Medicine, 2010, 88 : 981 - 986
  • [30] Empowering self-renewal and differentiation: the role of mitochondria in stem cells
    Rehman, Jalees
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2010, 88 (10): : 981 - 986
12345