Genomic evidence of lung carcinogenesis associated with coal smoke in Xuanwei area, China

被引：1

作者：

Honglei Zhang ^{[1
]}

Chao Liu ^{[2
]}

Li Li ^{[3
]}

Xu Feng ^{[1
]}

Qing Wang ^{[4
]}

Jihua Li ^{[5
]}

Shaobin Xu ^{[6
]}

Shuting Wang ^{[7
]}

Qianlu Yang ^{[8
]}

Zhenghai Shen ^{[8
]}

Jinhua Su ^{[9
]}

Xiaosan Su ^{[1
]}

Ruifen Sun ^{[1
]}

Xuhong Zhou ^{[1
]}

Junliang Wang ^{[1
]}

Yongchun Zhou ^{[2
]}

Baowei Jiao ^{[10
,11
,12
]}

Wanbao Ding ^{[13
]}

Xianbao Cao ^{[14
]}

Yue Wang ^{[15
]}

Yunchao Huang ^{[8
]}

Lianhua Ye ^{[8
]}

机构：

[1] Center for Scientific Research, Yunnan University of Chinese Medicine

[2] Department of Nuclear Medicine, Third Affiliated Hospital of Kunming Medical University,Yunnan Cancer Hospital

[3] Biotherapy Center,Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital

[4] Department of Oncology, Qujing First People's Hospital

[5] Qujing Center for Disease Control and Prevention

[6] Supercomputing Platform of Kunming Institute of Zoology, Kunming Biological Diversity Center of Instruments, Kunming Institute of Zoology, Chinese Academy of Sciences

[7] Department of Thoracic Surgery Ⅱ, Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital

[8] Department of Thoracic Surgery Ⅰ, Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital

[9] Department of Thoracic Surgery, Xuanwei People's Hospital

[10] State Key Laboratory of Genetic Resources and Evolution,Kunming Institute of Zoology, Chinese Academy of Sciences

[11] Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences

[12] KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences

[13] Department of Oncology, Yan'an Affiliated Hospital of Kunming Medical University

[14] Department of Otolaryngology, First People's Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology

[15] The Affiliated Hospital of Guizhou Medical University

来源：

NationalScienceReview | 2021年 / 8卷 / 12期

基金：

中国国家自然科学基金;

关键词：

D O I：

暂无

中图分类号：

R734.2 [肺肿瘤];

学科分类号：

摘要：

Xuanwei area, in southwestern China,harbors the highest female lung cancer rate in the country(Supplementary Table 1) [1]. Epidemiological studies have shown that lung cancer incidence in Xuanwei area is associated with the use of different types of local coal for household cooking and heating [2]. The genomic landscape of Xuanwei female adenocarcinoma(XWFA), the most distinctive feature of lung cancer in Xuanwei, has yet to be elucidated systematically. Here,we provide the fundamental resource of genomic datasets for further exploration of XWFA molecular mechanisms and development of targetable therapy.

引用

页码：15 / 19

页数：5

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