The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or naphthalene moiety

被引:0
|
作者
Guo Qiang Shangguan Lun Liang Huang Xiao Gang Qu a Department of Pharmacy
机构
关键词
Organogermanium sesquioxide; Synthesis; Cytotoxicity;
D O I
暂无
中图分类号
TP393 [计算机网络];
学科分类号
081201 ; 1201 ;
摘要
Four novel organogermanium sesquioxides with anthraquinone or naphthalene moiety were synthesized.The structures were characterized by IR,NMR and elemental analysis,and their cytotoxicities were evaluated against human chronic myeloid leukemia K562 cell lines.The cytotoxicity could be improved by the introduction of planar aromatic chromophore moiety to the parent compound,Ge-132.
引用
收藏
页码:1347 / 1350
页数:4
相关论文
共 50 条
  • [21] DESIGN, SYNTHESIS AND CYTOTOXIC ACTIVITY OF SOME NOVEL FLAVONES
    Venkatesh, Palani
    Prakash, Govindaraman
    Pavadai, Parasuraman
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2012, 3 (02): : 523 - 527
  • [22] Synthesis and biological evaluation of cytotoxic activity of novel anthracene L-rhamnopyranosides
    Song, Gaopeng
    Liu, Hongchun
    Zhang, Wei
    Geng, Meiyu
    Li, Yingxia
    BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 18 (14) : 5183 - 5193
  • [23] Design, synthesis, and antitumor evaluation of novel anthraquinone derivatives
    Larissa A. Oliveira
    Heloiza D. Nicolella
    Ricardo A. Furtado
    Nerilson M. Lima
    Denise C. Tavares
    Taís A. Corrêa
    Mauro V. Almeida
    Medicinal Chemistry Research, 2020, 29 : 1611 - 1620
  • [24] Design, synthesis, and antitumor evaluation of novel anthraquinone derivatives
    Oliveira, Larissa A.
    Nicolella, Heloiza D.
    Furtado, Ricardo A.
    Lima, Nerilson M.
    Tavares, Denise C.
    Correa, Tais A.
    Almeida, Mauro, V
    MEDICINAL CHEMISTRY RESEARCH, 2020, 29 (09) : 1611 - 1620
  • [25] Synthesis and Biological Activity of Anthraquinone-polyamine Derivatives
    Gan, Ying
    He, Lihua
    Zhang, Yahong
    Wang, Jianhong
    Zhao, Jin
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2014, 34 (03) : 589 - 595
  • [26] Synthesis and Insecticidal Activity of Novel Pyrazole Amides Containing an Isoxazole Moiety
    Zhang, Zichan
    Sun, Yang
    Hua, Sheng
    Xu, Baolin
    Zhang, Min
    Zhao, Qin
    Zheng, Dandan
    Wang, Yang
    Ju, Jianfeng
    Shi, Yujun
    Dai, Hong
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 43 (04) : 1435 - 1443
  • [27] Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety
    Wang, Yanwei
    Xu, Kehan
    Bai, Guojing
    Huang, Lei
    Wu, Qiuye
    Pan, Weihua
    Yu, Shichong
    MOLECULES, 2014, 19 (08) : 11333 - 11340
  • [28] Synthesis and antifungal activity of novel chiral α-aminophosphonates containing fluorine moiety
    Yang Song
    Gao Xing-Wen
    Diao Chun-Ling
    Song Bao-An
    Jin Lin-Hong
    Xu Guang-Fang
    Zhang Guo-Ping
    Wang Wei
    Hu De-Yu
    Zue Wei
    Zhou Xia
    Lu Ping
    CHINESE JOURNAL OF CHEMISTRY, 2006, 24 (11) : 1581 - 1588
  • [29] Design, Synthesis and Antifungal Activity of Novel Benzoylcarbamates Bearing a Pyridine Moiety
    Wan, Fu-Xian
    Wang, Jian-Hua
    Shi, Yan-Hua
    Niu, Li-Zhi
    Jiang, Lin
    APPLIED SCIENCES-BASEL, 2018, 8 (12):
  • [30] Synthesis and In Vitro Antitumor Activity of Novel Chromenones Bearing Benzothiazole Moiety
    El-Helw, Eman A.
    Derbala, Hamed A.
    El-Shahawi, Manal M.
    Salem, Marwa S.
    Ali, Mamdouh M.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2019, 45 (01) : 42 - 53