Embolization combined with endoscopic variceal ligation for the treatment of esophagogastric variceal bleeding in patients with cirrhosis

Background Esophagogastric variceal bleeding caused by cirrhosis is a kind of emergent condition in the clinic.Thisstudy was conducted to explore the therapeutic effect and superiority of embolization of gastric fundus varices combinedwith endoscopic variceal ligation(EVL)of esophageal varices for the treatment of patients with esophagogastric varicealbleeding caused by cirrhosis.Methods Totally 172 patients were diagnosed by endoscopic examination within 24 hours of hospitalization with activegastric fundus variceal bleeding and grade Ⅱ above esophageal varices caused by cirrhosis.Other causes leading toupper digestive tract bleeding were excluded.Patients were randomly divided into a control group(n=82)and a therapygroup(n=90)following a random number table method.For the former,embolization for gastric fundus varices wasperformed,then an EVL for esophageal varices was performed 2 months later.For the therapy group,embolization forgastric fundus varices and EVL for esophageal varices were performed at the same time.Results The rate of emergency hemostasis in the therapy group was 100.0%,higher than that in the control group(87.8%,P<0.05).The rate of early rebleeding in the therapy group was 6.7% while the rate in the control group was23.6%(P<0.05).No complications related to treatment occurred in both groups.Conclusion Embolization for gastric fundus varices combined with EVL for esophageal varices is a safe and effectivemethod for the treatment of patients with esophagogastric variceal bleeding caused by cirrhosis.