Effect of extract of Abrus precatorius on blood glucose concentration of alloxan induced diabetic Albino Wistar Rats

被引：0

作者：

Georgewill OA ^{[1
]}

Georgewill UO ^{[1
]}

机构：

[1] Department of Pharmacology and Toxicology

来源：

Asian Pacific Journal of Tropical Medicine | 2009年 / 2卷 / 06期

关键词：

Abrus precatorius; Hypoglycemia; Diabetes; Hyperglycemia;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

1008 ;

摘要：

Objective:To evaluate the effect of extract of Abrus precatorius on blood glucose of alloxan induced albino wistar rals.Methods:Experimental animals received daily oral administration of extract of Abrus precatorius for 14 days.The effect of 200 mg/kg dose was studied during the treatment period.Results:There was a significant reduction in blood glucose concentration(P < 0.05) with the mean blood glucose of the different groups as 5.0±0.3 for normal control,7.0±0.4 for diabetic control group and 4.0±0.2 for diabetic treated group. Conclusion:The findings of this study suggest that extract of Abrus precatorius has hypoglycemic effect.

引用

页码：16 / 17

页数：2

共 6 条

[1]

Commonly used Indian abortifacient plants with special reference to their teratologic effects in rats. Nath D,Sethi N,Singh RK,and Jain AK. Journal of Ethnopharmacology . 1992

[2]

Alternative therapies for type 2 diabetes. Lucy D,,Anoja SA,Chun SY. Alternative Medicine Review . 2002

[3]

The role of lipid in the study and diagnosis of diabetes mellitus. Ononogbu IC. Proceedings of the 1 st African Conference on Biochemistry of Lipids . 1998

[4]

Rain-Tree. http//www.rain - tree.com/abrus. htm . 2004

[5]

Guidance document on acute oral toxicity testing series on testing and assessment No.24. Origination for Economic Operation and Development. . 2001

[6]

Major manifestations of heart disease. Boon N A,Fox K A A,Bloomfield P. Davidson’’’’’’’’s principles and practice of medicine . 1999

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