Rosai-Dorfman disease in the spleen of a pediatric patient:A case report

被引：0

作者：

Hwaseong Ryu ^{[1
]}

Jae-Yeon Hwang ^{[1
]}

Yong-Woo Kim ^{[1
]}

Tae-Un Kim ^{[1
]}

Joo-Yeon Jang ^{[1
]}

Su-Eun Park ^{[2
]}

Eu-Jeen Yang ^{[2
]}

Dong-Hoon Shin ^{[3
]}

机构：

[1] Department of Radiology, Pusan National University Yangsan Hospital

[2] Department of Pediatrics, Pusan National University Children's Hospital

[3] Department of Pathology, Pusan National University Yangsan Hospital

来源：

World Journal of Clinical Cases | 2021年 / 9卷 / 21期

关键词：

Rosai–Dorfman disease; Sinus histiocytosis with massive lymphadenopathy; Ultrasonography; Computed tomography; Magnetic resonance imaging; Case report;

D O I：

暂无

中图分类号：

R725.7 [小儿消化系及腹部疾病];

学科分类号：

100202 ;

摘要：

BACKGROUND Rosai–Dorfman disease(RDD) is a rare histiocytic proliferation of unknown etiology commonly found in children and adolescents. The common manifestation of RDD is massive and painless bilateral cervical lymphadenopathy with extranodal disease. While extranodal involvement in RDD is common, the spleen is an infrequent site of disease.CASE SUMMARY We report a 10-mo-old female infant with RDD presenting multiple splenic masses without cervical lymphadenopathy. She had fever, and blood tests showed leukocytosis, anemia, and elevated erythrocyte sedimentation rate and Creactive protein. Ultrasound, computed tomography, and magnetic resonance images demonstrated multiple splenic masses. Despite antibiotic therapy, her symptoms were not relived. She underwent diagnostic splenectomy and was discharged with recovery.CONCLUSION In pediatric patients with refractory infectious symptoms or hematological abnormalities, clinicians should suspect RDD, even in patients without significant lymphadenopathy.

引用

页码：6032 / 6040

页数：9

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