MSU晶体介导的痛风性关节炎的炎症机制

被引：12
|
作者：
谢蓓蓓 [1 ]
苏厚恒 [2 ]
机构：
[1] 青岛大学医学院
[2] 青岛市市立医院免疫风湿科
来源：
中华临床医师杂志(电子版) | 2013年 / 7卷 / 16期
关键词：
痛风性关节炎; MSU; 晶体; 介导; 炎症机制;
D O I：
暂无
中图分类号：
R589.7 [嘌呤（Purine）代谢障碍];
学科分类号：
1002 ; 100201 ;
摘要：
痛风是一组由嘌呤代谢紊乱引起的以单钠尿酸盐(monosodium urate,MSU)晶体沉积为特征的疾病,以痛风性关节炎最常见。痛风性关节炎的急性发作是一种急性无菌性炎症反应。最近相关研究表明,白细胞介素(interleukin-1β,IL-1β)的生成在痛风性关节炎中起着非常重要的作用。NALP3(NACHT-LRR-PYD-containing proteins)参与了痛风性关节炎的
引用
收藏
页码：7518 / 7520
页数：3
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