Emerging applications of near-infrared fluorescent metal nanoclusters for biological imaging

被引：0

作者：

Jie Xu ^{[1
]}

Li Shang ^{[1
,2
]}

机构：

[1] State Key Laboratory of Solidification Processing,Center for Nano Energy Materials,School of Materials Science and Engineering,Northwestern Polytechnical University and Shaanxi Joint Laboratory of Graphene (NPU)

[2] NPU-QMUL Joint Research Institute of Advanced Materials and Structures (JRI-AMAS),Northwestern Polytechnical University

来源：

ChineseChemicalLetters | 2018年 / 29卷 / 10期

基金：

中国国家自然科学基金;

关键词：

Metal nanoclusters; Fluorescent probes; Cellular imaging; In vivo; Near-infrared;

D O I：

暂无

中图分类号：

O657.3 [光化学分析法（光谱分析法）]; TB383.1 [];

学科分类号：

070205 ; 070302 ; 080501 ; 081704 ; 1406 ;

摘要：

Fluorescent metal nanoclusters(MNCs) have recently emerged as a novel kind of promising fluorescent probes for biological imaging because of their ultrasmall core size(<2 nm), strong photoluminescence,facile availability and good biocompatibility. In this review, we provide an update on recent advances in the development of near infrared(NIR)-emitting MNCs in terms of synthesis strategies and bioimaging applications. We mainly focus on the utilization of NIR-emitting MNCs(including Au, Ag, Cu and alloy NCs) either as single modal imaging(fluorescence intensity-based imaging, fluorescence lifetime imaging, two-photon imaging) probes or as multimodal imaging(such as NIR fluorescence/X-ray computed tomography/magnetic resonance imaging, NIR fluorescence/photoacoustic imaging/magnetic resonance imaging, NIR fluorescence/single photon emission computed tomography) probes in biological cells and tissues. Finally, we give a brief outlook on the future challenges and prospects of developing NIR-emitting MNCs for bioimaging.

引用

页码：1436 / 1444

页数：9