Human immune repertoire in hepatitis B virus infection

被引：0
|
作者：
Qiao Zhan [1 ]
Jing-Hang Xu [1 ]
Yan-Yan Yu [1 ]
Emily Lo KK [2 ]
Felicianna [2 ]
Hani El-Nezami [2 ,3 ]
Zheng Zeng [1 ]
机构：
[1] Department of Infectious Diseases, Peking University First Hospital
[2] School of Biological Sciences, University of Hong Kong
[3] Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland
来源：
World Journal of Gastroenterology | 2021年 / 27卷 / 25期
基金：
中国国家自然科学基金;
关键词：
Immune repertoire; T-cell receptor; B-cell receptor; Hepatitis B virus; Chronic viral infection; High-throughput sequencing;
D O I：
暂无
中图分类号：
R512.62 [];
学科分类号：
100401 ;
摘要：
Hepatitis B virus(HBV) infection is a public health threat that affects 257 million people worldwide and can progress to liver cirrhosis, liver failure, and hepatocellular carcinoma. The HBV antigen-induced adaptive immune response plays an important role in HBV clearance. Immune repertoire sequencing(IRS) has been used to investigate the molecular mechanisms behind the immune system, find novel ways to treat HBV infection, and evaluate the genetic responses and immune characteristics of individuals infected by HBV or immunized by HBV vaccine. This review summarizes the human immune repertoire analysis methodology, and the application of the IRS in the prediction of HBV infection progression, treatment, and vaccination.
引用
收藏
页码：3790 / 3801
页数：12
相关论文
共 50 条
  • [21] Human hepatitis B virus and hepatocellular carcinoma .1. Experimental infection of tree shrews with hepatitis B virus
    Yan, RQ
    Su, JJ
    Huang, DR
    Gan, YC
    Yang, C
    Huang, GH
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 1996, 122 (05) : 283 - 288
  • [22] The innate immune response to hepatitis B virus infection: Implications for pathogenesis and therapy
    Chang, Jinhong
    Block, Timothy M.
    Guo, Ju-Tao
    ANTIVIRAL RESEARCH, 2012, 96 (03) : 405 - 413
  • [23] Clinical implication of immune checkpoint inhibitor on the chronic hepatitis B virus infection
    Hagiwara, Satoru
    Nishida, Naoshi
    Ida, Hiroshi
    Ueshima, Kazuomi
    Minami, Yasunori
    Takita, Masahiro
    Aoki, Tomoko
    Morita, Masahiro
    Chishina, Hirokazu
    Komeda, Yoriaki
    Yoshida, Akihiro
    Hayashi, Hidetoshi
    Nakagawa, Kazuhiko
    Kudo, Masatoshi
    HEPATOLOGY RESEARCH, 2022, 52 (09) : 754 - 761
  • [24] Immune Control of Hepatitis B Virus
    Bauer, Tanja
    Sprinzl, Martin
    Protzer, Ulrike
    DIGESTIVE DISEASES, 2011, 29 (04) : 423 - 433
  • [25] Immune Evasion Strategies during Chronic Hepatitis B and C Virus Infection
    Ortega-Prieto, Ana Maria
    Dorner, Marcus
    VACCINES, 2017, 5 (03)
  • [26] Immunopathology of Hepatitis B Virus Infection
    Tsai, Hsiu-Ting
    Tsai, Tzu-Hsin
    Lu, Tsong-Ming
    Yang, Chi-Chiang
    INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2008, 27 (06) : 427 - 446
  • [27] Immunobiology of hepatitis B virus infection
    Isogawa, Masanori
    Tanaka, Yasuhito
    HEPATOLOGY RESEARCH, 2015, 45 (02) : 179 - 189
  • [28] Pregnancy and hepatitis B virus infection
    Cabezas-Sanchez, Cesar
    Donayre, Fernando
    REVISTA PERUANA DE GINECOLOGIA Y OBSTETRICIA, 2010, 56 (03): : 183 - 192
  • [29] Update on hepatitis B virus infection
    Chan Ran You
    Sung Won Lee
    Jeong Won Jang
    Seung Kew Yoon
    World Journal of Gastroenterology, 2014, (37) : 13293 - 13305
  • [30] Hepatitis B virus infection in Indonesia
    Yoshihiko Yano
    Takako Utsumi
    Maria Inge Lusida
    Yoshitake Hayashi
    World Journal of Gastroenterology, 2015, (38) : 10714 - 10720
12345