miR-125b promotes proliferation of human acute myeloid leukemia cells by targeting Bak1

被引:0
|
作者
曾巧慧 [1 ]
机构
[1] Dept Outpatient,Guangzhou Women & Children Med Center
关键词
gene; cell; AML; miR-125b promotes proliferation of human acute myeloid leukemia cells by targeting Bak1; UTR;
D O I
暂无
中图分类号
R733.7 [白血病];
学科分类号
摘要
Objective To investigate miR-125b regulation mechanism by identifying miR-125b target genes and itsfunction in acute myeloid leukemia(AML).Methods The bioinformatics software and database were applied to predict and analyze target genes of miR-125b.The vector contained the target gene 3’-UTR portion cloned into a luciferase reporter
引用
收藏
页码:54 / 55
页数:2
相关论文
共 50 条
  • [21] MiR-125b protects against ethanol-induced apoptosis in neural crest cells and mouse embryos by targeting Bak 1 and PUMA
    Chen, Xiaopan
    Liu, Jie
    Feng, Wen-ke
    Wu, Xiaoyang
    Chen, Shao-yu
    EXPERIMENTAL NEUROLOGY, 2015, 271 : 104 - 111
  • [22] MiR-125b-mediated BAK1 downregulation contributes to drug-resistance in gastric cancer cells
    Hu, Xiao
    Bai, Zhigang
    Liu, Zhao
    Zhang, Zhongtao
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 11 (04): : 3156 - 3163
  • [23] MiR-125b orchestrates cell proliferation, differentiation and migration in neural stem/progenitor cells by targeting Nestin
    Yi Cui
    Zhifeng Xiao
    Jin Han
    Jie Sun
    Wenyong Ding
    Yannan Zhao
    Bing Chen
    Xiaoran Li
    Jianwu Dai
    BMC Neuroscience, 13
  • [24] miR-125b regulates the proliferation of glioblastoma stem cells by targeting E2F2
    Wu, Ning
    Xiao, Lin
    Zhao, Xiangzhong
    Zhao, Jin
    Wang, Jianpeng
    Wang, Fengxia
    Cao, Shousong
    Lin, XiuKun
    FEBS LETTERS, 2012, 586 (21) : 3831 - 3839
  • [25] MiR-125b orchestrates cell proliferation, differentiation and migration in neural stem/progenitor cells by targeting Nestin
    Cui, Yi
    Xiao, Zhifeng
    Han, Jin
    Sun, Jie
    Ding, Wenyong
    Zhao, Yannan
    Chen, Bing
    Li, Xiaoran
    Dai, Jianwu
    BMC NEUROSCIENCE, 2012, 13
  • [26] miR-125a regulates cell cycle, proliferation, and apoptosis by targeting the ErbB pathway in acute myeloid leukemia
    Ufkin, Melanie L.
    Peterson, Sarah
    Yang, Xuehui
    Driscoll, Heather
    Duarte, Christine
    Sathyanarayana, Pradeep
    LEUKEMIA RESEARCH, 2014, 38 (03) : 402 - 410
  • [27] Mir-23a and mir-125b regulate neural stem/progenitor cell proliferation by targeting Musashi1
    Gioia, Ubaldo
    Di Carlo, Valerio
    Caramanica, Pasquale
    Toselli, Camilla
    Cinquino, Antonella
    Marchioni, Marcella
    Laneve, Pietro
    Biagioni, Stefano
    Bozzoni, Irene
    Cacci, Emanuele
    Caffarelli, Elisa
    RNA BIOLOGY, 2014, 11 (09) : 1105 - 1112
  • [28] miR-125b Promotes the Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma (OSCC)
    Yan, Yan
    Wu, Zengbo
    Chen, Xianzhuo
    JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, 2022, 12 (12) : 2438 - 2443
  • [29] MicroRNA miR-125b induces senescence in human melanoma cells
    Glud, Martin
    Manfe, Valentina
    Biskup, Edyta
    Holst, Line
    Dirksen, Anne Marie Ahlburg
    Hastrup, Nina
    Nielsen, Finn C.
    Drzewiecki, Krzysztof T.
    Gniadecki, Robert
    MELANOMA RESEARCH, 2011, 21 (03) : 253 - 256
  • [30] miR-125b suppresses cellular proliferation by targeting c-FLIP in gallbladder carcinoma
    Zong, Huajie
    Zhou, Huading
    Xiang, Yang
    Wu, Gang
    ONCOLOGY LETTERS, 2019, 18 (06) : 6822 - 6828