miR-125b promotes proliferation of human acute myeloid leukemia cells by targeting Bak1

被引：0
作者：
曾巧慧 [1 ]
机构：
[1] Dept Outpatient,Guangzhou Women & Children Med Center
来源：
ChinaMedicalAbstracts(InternalMedicine) | 2014年 / 31卷 / 01期
关键词：
gene; cell; AML; miR-125b promotes proliferation of human acute myeloid leukemia cells by targeting Bak1; UTR;
D O I：
暂无
中图分类号：
R733.7 [白血病];
学科分类号：
100214 ;
摘要：
Objective To investigate miR-125b regulation mechanism by identifying miR-125b target genes and itsfunction in acute myeloid leukemia(AML).Methods The bioinformatics software and database were applied to predict and analyze target genes of miR-125b.The vector contained the target gene 3’-UTR portion cloned into a luciferase reporter
引用
收藏
页码：54 / 55
页数：2
相关论文
共 50 条
  • [1] MiR-125b Expression Affects the Proliferation and Apoptosis of Human Glioma Cells by Targeting Bmf
    Xia, Hong-Fei
    He, Tian-Zhu
    Liu, Chun-Mei
    Cui, Yi
    Song, Pei-Pei
    Jin, Xiao-Hua
    Ma, Xu
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2009, 23 (4-6) : 347 - 358
  • [2] miR-125b regulates the proliferation of glioblastoma stem cells by targeting E2F2
    Wu, Ning
    Xiao, Lin
    Zhao, Xiangzhong
    Zhao, Jin
    Wang, Jianpeng
    Wang, Fengxia
    Cao, Shousong
    Lin, XiuKun
    FEBS LETTERS, 2012, 586 (21) : 3831 - 3839
  • [3] MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo
    Jiang, Feizhou
    Liu, Te
    He, Yinyan
    Yan, Qin
    Chen, Xiaoyue
    Wang, Hui
    Wan, Xiaoping
    BMC CANCER, 2011, 11
  • [4] MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2
    Xu, Ning
    Brodin, Petter
    Wei, Tianling
    Meisgen, Florian
    Eidsmo, Liv
    Nagy, Nikoletta
    Kemeny, Lajos
    Stahle, Mona
    Sonkoly, Eniko
    Pivarcsi, Andor
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 (07) : 1521 - 1529
  • [5] miR-1290 PROMOTES PROLIFERATION AND SUPPRESSES APOPTOSIS IN ACUTE MYELOID LEUKEMIA BY TARGETING FOXG1/SOCS3
    Sun, Y.
    Ju, X-L.
    Li, D.
    Zhou, P-P.
    Li, X.
    Luo, R-H.
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2019, 33 (06) : 1703 - 1713
  • [6] RACK1 promotes the proliferation of THP1 acute myeloid leukemia cells
    Dalin Zhang
    Qingyang Wang
    Ting Zhu
    Junxia Cao
    Xueying Zhang
    Jing Wang
    Xiaoqian Wang
    Yan Li
    Beifen Shen
    Jiyan Zhang
    Molecular and Cellular Biochemistry, 2013, 384 : 197 - 202
  • [7] RACK1 promotes the proliferation of THP1 acute myeloid leukemia cells
    Zhang, Dalin
    Wang, Qingyang
    Zhu, Ting
    Cao, Junxia
    Zhang, Xueying
    Wang, Jing
    Wang, Xiaoqian
    Li, Yan
    Shen, Beifen
    Zhang, Jiyan
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2013, 384 (1-2) : 197 - 202
  • [8] MiR-125b Targeting MCL1 Inhibits Proliferation of Gastric Cancer Cell Line MGC-803
    Hu Ze-Gang
    Wu Shi-Hua
    Liu Zhong-Yuan
    Xie Li-Ming
    Zhang He-Liang
    Xiao Xuan
    Zhang Zhi-Wei
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 45 (05) : 544 - 552
  • [9] miR-126 promotes the growth and proliferation of leukemia stem cells by targeting DNA methyltransferase 1
    Ding, Qian
    Wang, Qing
    Ren, Yi
    Zhu, Hongqian
    Huang, Zhujun
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2018, 11 (07): : 3454 - 3462
  • [10] miR-196a Promotes Proliferation of Mammary Epithelial Cells by Targeting CDKN1B
    Chen, Guanhe
    Sun, Wenqiang
    Li, Yuchao
    Li, Mengze
    Jia, Xianbo
    Wang, Jie
    Lai, Songjia
    ANIMALS, 2023, 13 (23):
12345