miR-125b promotes proliferation of human acute myeloid leukemia cells by targeting Bak1

被引：0
|
作者：
曾巧慧 [1 ]
机构：
[1] Dept Outpatient,Guangzhou Women & Children Med Center
来源：
China Medical Abstracts(Internal Medicine) | 2014年 / 31卷 / 01期
关键词：
gene; cell; AML; miR-125b promotes proliferation of human acute myeloid leukemia cells by targeting Bak1; UTR;
D O I：
暂无
中图分类号：
R733.7 [白血病];
学科分类号：
摘要：
Objective To investigate miR-125b regulation mechanism by identifying miR-125b target genes and itsfunction in acute myeloid leukemia(AML).Methods The bioinformatics software and database were applied to predict and analyze target genes of miR-125b.The vector contained the target gene 3’-UTR portion cloned into a luciferase reporter
引用
收藏
页码：54 / 55
页数：2
相关论文
共 50 条
  • [1] miR-125b regulates cell progression in chronic myeloid leukemia via targeting BAK1
    Li, Quan
    Wu, Yaohui
    Zhang, Yongkang
    Sun, Huapeng
    Lu, Zhaoli
    Du, Ke
    Fang, Shanshan
    Li, Weiming
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2016, 8 (02): : 447 - 459
  • [2] Downregulation of miR-125b suppress cell viability and induces cell apoptosis in human myeloid leukemia via targeting Bak1
    Lin, Dongjing
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2019, 125 : 97 - 97
  • [3] MiR-125b inhibits cardiomyocyte apoptosis by targeting BAK1 in heart failure
    Bei Zhang
    Shanyong Mao
    Xingde Liu
    Sha Li
    Haiyan Zhou
    Ying Gu
    Wupeng Liu
    Lei Fu
    Chunyan Liao
    Pengzhen Wang
    Molecular Medicine, 2021, 27
  • [4] MiR-125b inhibits cardiomyocyte apoptosis by targeting BAK1 in heart failure
    Zhang, Bei
    Mao, Shanyong
    Liu, Xingde
    Li, Sha
    Zhou, Haiyan
    Gu, Ying
    Liu, Wupeng
    Fu, Lei
    Liao, Chunyan
    Wang, Pengzhen
    MOLECULAR MEDICINE, 2021, 27 (01)
  • [5] miR-125b inhibitor enhance the chemosensitivity of glioblastoma stem cells to temozolomide by targeting Bak1
    Chen, Jian
    Fu, Xingli
    Wan, Yi
    Wang, Zhimin
    Jiang, Dongyi
    Shi, Lei
    TUMOR BIOLOGY, 2014, 35 (07) : 6293 - 6302
  • [6] Mir-125b confers the resistance of cancer cells to Taxol through suppression of Bak1
    Zhou, Ming
    Zhao, Yuhua
    Ding, Yan
    Liu, Hao
    Liu, Zixing
    Xi, Yaguang
    Xiong, Wei
    Li, Guiyuan
    Lu, Jianrong
    Fodstad, Oystein
    Riker, Adam I.
    Tan, Ming
    CANCER RESEARCH, 2010, 70
  • [7] OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway
    Y-D Wang
    N Cai
    X-L Wu
    H-Z Cao
    L-L Xie
    P-S Zheng
    Cell Death & Disease, 2013, 4 : e760 - e760
  • [8] OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway
    Wang, Y-D
    Cai, N.
    Wu, X-L
    Cao, H-Z
    Xie, L-L
    Zheng, P-S
    CELL DEATH & DISEASE, 2013, 4 : e760 - e760
  • [9] Assessment of mechanism of Ganoderma lucidum neutral triterpenes mediating bone marrow mesenchymal stem cells with high expression of miR-125b targeting Bak1 gene in leukemia cell proliferation and apoptosis
    Shen, Yang
    Chen, Junyi
    Zhu, Ye
    MATERIALS EXPRESS, 2023, 13 (08) : 1383 - 1391
  • [10] miR-125b promotes cell proliferation by directly targeting Lin28 in glioblastoma stem cells with low expression levels of miR-125b
    Wan, Yi
    Sun, Guan
    Wang, Zhimin
    Guo, Jun
    Shi, Lei
    NEUROREPORT, 2014, 25 (05) : 289 - 296
12345