Heat shock protein 90 is a potential therapeutic target for ameliorating skeletal muscle abnormalities in Parkinson's disease

被引：0
作者：
Nour Erekat [1 ]
Ahed Al-Khatib [2 ]
Muhammed Al-Jarrah [3 ,4 ]
机构：
[1] Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology (JUST)
[2] Department of Pathology, Faculty of Medicine, Jordan University of Science and Technology
[3] Department of Rehabilitation Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology
[4] Fatima College of Health Sciences (FCHS)
来源：
Neural Regeneration Research | 2014年 / 9卷 / 06期
关键词：
nerve regeneration; heat shock protein 90; Parkinson’s disease; exerecise; soleus muscle; gastrocnemius muscle; skeletal muscle; treadmill excise; neural regeneration;
D O I：
暂无
中图分类号：
R742.5 [震颤麻痹综合征];
学科分类号：
1002 ;
摘要：
Previous studies have confirmed that heat shock protein 90 overexpression can lead to dopaminergic neuronal death. This study was designed to further investigate what effects are produced by heat shock protein 90 after endurance exercise training. Immunohistochemistry results showed that exercise training significantly inhibited heat shock protein 90 overexpression in the soleus and gastrocnemius in Parkinson’s disease rats, which is a potential therapeutic target for ameliorating skeletal muscle abnormalities in Parkinson’s disease.
引用
收藏
页码：616 / 621
页数：6
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