STUDY ON SUSCEPTIBILITY OF VARIOUS TISSUES TO CHEMICAL CARCINOGENS USING AUTORADIOGRAPHIC DETECTION OF UDS

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STUDY ON SUSCEPTIBILITY OF VARIOUS TISSUES TO CHEMICAL CARCINOGENS USING AUTORADIOGRAPHIC DETECTION OF UDS; MNNG;
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The methods of in vitro and in vivo-in vitro combinationassay for autoradiographic detection of unscheduled DNAsynthesis(UDS)induced by chemical carcinogens wasestablished.To estimate the reliability of these assays,UDS in tissues slices was measured with the establishedmethods after exposure to MNNG and dimethylnitrosamine(DMN)in vitro or in vivo respectively.To study thesusceptibility of various tissues to chemicals,UDS induced
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页码:269 / 269
页数:1
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