Of Monkeys and Men: New Insights into Using Chinese Rhesus Macaque as a Viable Model of Human Aging

被引:0
|
作者
Andrew Willden
机构
关键词
New Insights into Using Chinese Rhesus Macaque as a Viable Model of Human Aging; Of Monkeys and Men;
D O I
暂无
中图分类号
R339.38 [];
学科分类号
071008 ;
摘要
Of all human conditions,aging and death are perhaps the most universal.Unfortunately death among elderly populations is often a drawn out and painful affair,as advanced age is accompanied by marked rises in morbidity and mortality due to infectious diseases.Precisely why this is the case has been subject to a great deal of speculation,but one commonly held explanation is referred to as immunosenescence,where the human body undergoes a remodeling of both innate and adaptive immune responses,and some functions are enhanced while others diminished.Both responses are key to the human immune systems,which fights off outside
引用
收藏
页码:256 / 257
页数:2
相关论文
共 50 条
  • [31] IDENTIFYING AND CATALOGUING HUMAN-RHESUS MACAQUE GENE ORTHOLOGS USING HETEROSPECIFIC SNPS
    Kanthaswamy, S.
    Ng, J.
    Ross, C.
    Trask, J. S.
    Smith, D. G.
    AMERICAN JOURNAL OF PRIMATOLOGY, 2012, 74 : 63 - 63
  • [32] Identifying human-rhesus macaque gene orthologs using heterospecific SNP probes
    Kanthaswamy, Sree
    Ng, Jillian
    Ross, Cody T.
    Trask, Jessica Satkoski
    Smith, David Glenn
    Buffalo, Vince S.
    Fass, Joseph N.
    Lin, Dawei
    GENOMICS, 2013, 101 (01) : 30 - 37
  • [33] INFLAMMATORY PROFILE IN RESPONSE TO UNCONTROLLED HEMORRHAGE IN A NON-HUMAN PRIMATE (RHESUS MACAQUE) MODEL
    Paredes, R. M.
    Vernon, P. J.
    Crossland, R.
    Macko, A. R.
    Burdette, A. J.
    Lucca, J. J. Dalle
    Sheppard, F. R.
    SHOCK, 2015, 43 (06): : 112 - 112
  • [34] INFLAMMATORY PROFILE IN RESPONSE TO UNCONTROLLED HEMORRHAGE IN A NON-HUMAN PRIMATE (RHESUS MACAQUE) MODEL
    Burdette, Alexander J.
    Paredes, Ruth Madelaine
    Crossland, Randy F.
    Macko, Antoni R.
    Aden, James
    Sheppard, Forest R.
    SHOCK, 2016, 46 (03): : 115 - 122
  • [35] Nigrostriatal degeneration and impaired motor function in aged rhesus monkeys: A model of human aging and early Parkinson's disease (PD) for neural transplantation
    Emborg, ME
    Ma, SY
    Mufson, EJ
    Levey, A
    Holden, JE
    Brown, D
    Kordower, JH
    EXPERIMENTAL NEUROLOGY, 1998, 153 (02) : 389 - 389
  • [36] MOTHER-INFANT SEPARATION IN RHESUS-MONKEYS AS A MODEL OF HUMAN DEPRESSION - RECONSIDERATION
    LEWIS, JK
    MCKINNEY, WT
    YOUNG, LD
    KRAEMER, GW
    ARCHIVES OF GENERAL PSYCHIATRY, 1976, 33 (06) : 699 - 705
  • [37] Rapid, accurate mapping of transgene integration in viable rhesus macaque embryos using enhanced-specificity tagmentation-assisted PCR
    Ryu, Junghyun
    Chan, William
    Wettengel, Jochen M.
    Hanna, Carol B.
    Burwitz, Benjamin J.
    Hennebold, Jon D.
    Bimber, Benjamin N.
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2022, 24 : 241 - 254
  • [38] TRAUMA-INDUCED COAGULOPATHY IN A NON-HUMAN PRIMATE (RHESUS MACAQUE) MODEL OF UNCONTROLLED HEMORRHAGE
    Fryer, D. M.
    Macko, A. R.
    Crossland, R.
    Fedyk, C. G.
    Scherer, M. R.
    Cap, A. P.
    Sheppard, F. R.
    SHOCK, 2015, 43 (06): : 71 - 71
  • [39] Insights into Aβ and presenilin from a canine model of human brain aging
    Head, E
    Torp, R
    NEUROBIOLOGY OF DISEASE, 2002, 9 (01) : 1 - 10
  • [40] EVALUATION OF THE ANGELCHIK ANTIREFLUX PROSTHESIS USING A MODEL FOR ESOPHAGEAL REFLUX IN RHESUS-MONKEYS
    COHEN, DJ
    BENJAMIN, SB
    GRAEBER, GM
    CASTELL, DO
    PATRICK, DH
    CORDOVA, C
    DACHMAN, A
    FRIEDMAN, A
    ANNALS OF THORACIC SURGERY, 1986, 41 (02): : 135 - 142