Study of the Correlation between Plasma Homocysteine and Coronary Artery Disease

<正> Objectives This paper isto investigate the correlation between plasma total ho-mocysteine (tHcy) and coronary artery disease(CAD).Methods Using high performance liquid chromato-graph to determine the level of plasma tHcy in 215cases, and they were selective coronare angiography.107 cases were determined to have CAD with at leastone vessel was narrowed <50%. 108 cases were non-narrowed, and they were listed as controls. Their 10parameters such as sex, age, body height, body weightand blood lipid etc. were no statistical difference be-tween two groups. Results The plasma tHcy 11.20(±5.56) μmol/L of the CAD group and 11.46(±5.50) ofthe control group, between them there was no statisti-cal difference (P>0.5). 12.17 (±6.25)μmol/L tHcyconcentration of the male was significant higher than9.60(±5.10) of the female (P<0.001). ConclusionsNone of correlation between the plasma tHcy andCAD can be found, and the tHcy of male is higherthan that of female.