高迁移率族蛋白B1(HMGB1)和肿瘤

被引：1
|
作者：
章俊强
梅晓冬
机构：
[1] 安徽医科大学附属省立医院呼吸科
来源：
临床肺科杂志 | 2011年 / 16卷 / 12期
关键词：
HMGB1; 核蛋白; B1; 蛋白聚糖; RAGE; 凋亡细胞; 肿瘤细胞; 结肠直肠癌; 远处转移;
D O I：
暂无
中图分类号：
R730.2 [肿瘤病理学、病因学];
学科分类号：
摘要：
<正>HMGB1是一种非常古老的核蛋白,在悠久的进化史中具有高度保守的特点,哺乳动物中HMGB1具有99%的同源特质[1]。HMGB1作为一种核蛋白可以稳定核小体,调节多种基因的转录,同时作为一种炎症因子,它可被多种炎症细胞释放或分泌,参与多种疾病的发生,发展和转归,如脓毒症,缺血-
引用
收藏
页码：1930 / 1931
页数：2
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