The cholera epidemic of 2004 in Douala, Cameroon: A lesson learned

被引:0
作者
Christoph J.Hemmer [1 ]
Jürgen N?ske
Stefan Finkbeiner [1 ]
Günter Kundt [3 ]
Emil C.Reisinger [1 ]
机构
[1] University of Rostock, Faculty of Medicine, Department of Tropical Medicine and Infectious Diseases
[2] Gesellschaft für Internationale Zusammenarbeit  3. University of Rostock, Faculty of Medicine, Institute of Biostatistics and Informatics in Medicine and Ageing Research
关键词
Cholera; Douala; Cameroon; Case fatality rate; Staff-to-patients ratio;
D O I
暂无
中图分类号
R516.5 [霍乱、副霍乱]; R181.3 [流行病学各论];
学科分类号
100401 ;
摘要
Objective: To describe the outbreak of 2004 with a view of retrospectively identifying factors that might explain the low case fatality rate. Methods: Outbreak data from 4 915 Cholera patients from registers of the Regional Health Delegation in Douala were analyzed using SPSS. Chi-square test, univariate and multivariate analysis were applied. Results: The outbreak started January 2004, peaking at 187 cases per week in February. After a decrease in April, case numbers rose to 688 cases per week in June. The outbreak was over in September 2004( <10 cases per week). The case fatality rate was higher in treatment centers with fewer than one nurse per two patients, than in those with more nursing staff. A temporary staff reduction after the first wave of the epidemic was associated with the increase of the case fatality rate during the second wave. This increase was reversed after re-instating full staff capacity.Conclusions: Providing sufficient nursing staff helps to lower the case fatality rate of cholera. Besides a lack of staff, age above 40 years is a risk factor for death in this disease.
引用
收藏
页码:347 / 352
页数:6
相关论文
共 5 条
  • [1] Distribution and molecular characteristics of Vibrio cholerae O1 El Tor isolates recovered in Guangdong Province, China, 1961–2013[J] . Baisheng Li,Rongfeng Chen,Duochun Wang,Hailing Tan,Bixia Ke,Dongmei He,Changwen Ke,Yonghui Zhang. Infection, Genetics and Evolution . 2016
  • [2] National Surveillance Data on the Epidemiology of Cholera in Cameroon[J] . L. Dempouo Djomassi,Bradford D. Gessner,G. Ondobo Andze,G. A. Etoundi Mballa. Journal of Infectious Diseases . 2013 (supp)
  • [3] Evolution of new variants of Vibrio cholerae O1[J] . Ashrafus Safa,G. Balakrish Nair,Richard Y.C. Kong. Trends in Microbiology . 2009 (1)
  • [4] évolution de la sensibilité de Vibrio cholerae 01 après utilisation prolongée d'antibiotiques en traitement et en prophylaxie au cours de l'épidémie de choléra de Douala (Cameroun) 2004[J] . E. Guévart,J. Solle,A. Mouangue,J. Noeske,A. Bita,M.-C. Fonkoua,M. Ndayo Wouafo. Médecine et Maladies Infectieuses . 2006 (6)
  • [5] Randomised Double Blind Trial Of Single Dose Doxycycline For Treating Cholera In Adults[J] . A. N. Alam,N. H. Alam,T. Ahmed,D. A. Sack. BMJ: British Medical Journal . 1990 (6740)