Detection of Messenger RNA for Gonadotropin-Releasing Hormone (GnRH) but not for GnRH Receptors in Rat Pancreas

被引：0

作者：

王雷

谢莉萍

黄威权

张荣庆

机构：

来源：

Tsinghua Science and Technology | 2001年 / 03期

关键词：

gonadotrophin releasing hormone; gonadotrophin releasing hormone receptor; gene expression; pancreas; reverse transcriptase polymerase chain reaction (RT PCR); mRNA;

D O I：

暂无

中图分类号：

Q522 [核糖（醣）核酸（RNA）];

学科分类号：

071010 ; 081704 ;

摘要：

Although gonadotropin releasing hormone (GnRH), GnRH like molecule, and GnRH receptor (GnRH R) have been reported to exist in several tissues other than brain or anterior pituitary, there are no reports concerning GnRH or GnRH R gene expression in a normal pancreatic gland. In order to define the production of GnRH as well as GnRH R in the pancreatic gland, we examined their gene expression in various developmental stages of rat pancreas using the reverse transcriptase polymerase chain reaction (RT PCR). GnRH mRNA transcripts were found in pancreas of male and female rats at different ages, expressing at about the same level, whereas GnRH R mRNA transcripts could not be detected in any rat pancreatic gland samples. These results suggest a possible biological role of GnRH in rodent pancreas. 

引用

页码：212 / 215

页数：4

共 12 条

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