Studies on the mechanism of immune recognition and regulation in the innate immunity against infection

With the long-term continuous and strong support from the National Natural Science Foundation of China,the research team headed by Prof.Cao Xuetao has conducted a series of innovative studies focusing on the mechanisms of immune recognition and regulation in the innate immune response against infection,and discovered several innate receptors and signaling molecules for viral recognition,revealed the signal transduction mechanism.In the past 5 years,they published 8 papers in Nature Immunology to report their main research findings.In January 2013,Cell published their important discovery on the molecular mechanism of RNA virus to escape from innate immune response,which may open up a new horizon for antiviral drug design and vaccine development.Because of his internationally competitive accomplish-