Design,synthesis and antimicrobial activities of 1,2,3-triazole derivatives

被引：0

作者：

Xu Zhao aBo Wei Lu bJun Rui Lu aChun Wei Xin aJian Fa Li aYa Liu a a College of Chemistry and Chemical EngineeringTianjin University of TechnologyTianjin China b College of ChemistryNankai UniversityTianjin China ^{[300384
,300071
]}

机构：

来源：

Chinese Chemical Letters | 2012年 / 23卷 / 08期

关键词：

1-(4-Substituted phenyl)-4-(4-bromophenyl)-5-(halo-o-hydroxyphenyl)imino-1,2,3-triazoles; 1-(4-Substituted phenyl)-4-(4-bromophenyl)-5-amino-1,2,3-triazoles; Synthesis; Antimicrobial activity;

D O I：

暂无

中图分类号：

O626 [杂环化合物];

学科分类号：

070303 ; 081704 ;

摘要：

Fifteen 1-(4-substituted phenyl)-4-(4-bromophenyl)-5-(halo-o-hydroxyphenyl)imino-1,2,3-triazoles were designed and synthesized based on rational combination of 1,2,3-triazoles and(halo)o-hydroxyphenyl group according to the superposition principle of reinforcement of biological activities.All the compounds were tested to an in vitro antimicrobial screening against M.a.and E.c..Compounds IIe-IIo exhibited more potent antimicrobial activities against M.a.and E.c.than triclosan and fluconazole,which provided valuable information to further study of novel antimicrobial research.

引用

页码：933 / 935

页数：3