Synthesis and Antitumor Activity of C-2/C-10 Modified Analogues of Docetaxel

被引:0
作者
Wei Shuo FANG Hong Yan LIU Qi Cheng FANG Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Beijing [100050 ]
机构
关键词
Paclitaxel; docetaxel; 2α-amido analogues; 10-propionate;
D O I
暂无
中图分类号
O621 [有机化学一般性问题];
学科分类号
070303 ; 081704 ;
摘要
Four 10-propionyl docetaxel analogues (11a-d) with 2α-amido substituents were prepared, and their antitumor activity against three solid tumor cell lines and their drug-resistant counterparts were determined.
引用
收藏
页码:38 / 40
页数:3
相关论文
共 2 条
[1]  
D.G.I. Kingston,Chem. Commun . 2001
[2]  
K.C.Nicolaou,J.Renaud,P.G.Nantermet,E.A.Couladouros,R.K.Guy,W.Wrasidlo. J.Am.Chem.Soc . 1995