Genetically encoded neural activity indicators

被引：1
作者：
Fang Luo [1 ]
Yin Wei [1 ]
Ziyue Wang [1 ]
Minmin Luo [2 ]
Ji Hu [1 ]
机构：
[1] School of Life Science and Technology, ShanghaiTech University
[2] National Institute of Biological Sciences
来源：
Brain Science Advances | 2018年 / 4卷 / 01期
关键词：
calcium imaging; neural activity; membrane potential probe; neurotransmitter reporter;
D O I：
暂无
中图分类号：
Q42 [神经生理学];
学科分类号：
071006 ;
摘要：
Recent years have witnessed the fascinating development of imaging approaches to studying neural activities; this progress has been based on an influx of ideas and methods from molecular biology and optical engineering. Here we review the design and application of genetically encoded indicators for calcium ions, membrane potential and neurotransmitters. We also summarize common strategies for the design and optimization of genetically encoded neural activity indicators.
引用
收藏
页码：1 / 15
页数：15
相关论文
共 35 条
  • [1] A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice[J] . Fangmiao Sun,Jianzhi Zeng,Miao Jing,Jingheng Zhou,Jiesi Feng,Scott F. Owen,Yichen Luo,Funing Li,Huan Wang,Takashi Yamaguchi,Zihao Yong,Yijing Gao,Wanling Peng,Lizhao Wang,Siyu Zhang,Jiulin Du,Dayu Lin,Min Xu,Anatol C. Kreitzer,Guohong Cui,Yulong Li.Cell . 2018 (2)
  • [2] Lighting up the brain: genetically encoded fluorescent sensors for imaging neurotransmitters and neuromodulators[J] . Huan Wang,Miao Jing,Yulong Li.Current Opinion in Neurobiology . 2018
  • [3] A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters
    Piatkevich, Kiryl D.
    Jung, Erica E.
    Straub, Christoph
    Linghu, Changyang
    Park, Demian
    Suk, Ho-Jun
    Hochbaum, Daniel R.
    Goodwin, Daniel
    Pnevmatikakis, Eftychios
    Pak, Nikita
    Kawashima, Takashi
    Yang, Chao-Tsung
    Rhoades, Jeffrey L.
    Shemesh, Or
    Asano, Shoh
    Yoon, Young-Gyu
    Freifeld, Limor
    Saulnier, Jessica L.
    Riegler, Clemens
    Engert, Florian
    Hughes, Thom
    Drobizhev, Mikhail
    Szabo, Balint
    Ahrens, Misha B.
    Flavell, Steven W.
    Sabatini, Bernardo L.
    Boyden, Edward S.
    [J]. NATURE CHEMICAL BIOLOGY, 2018, 14 (04) : 352 - +
  • [4] A Bright and Fast Red Fluorescent Protein Voltage Indicator That Reports Neuronal Activity in Organotypic Brain Slices
    Abdelfattah, Ahmed S.
    Farhi, Samouil L.
    Zhao, Yongxin
    Brinks, Daan
    Zou, Peng
    Ruangkittisakul, Araya
    Platisa, Jelena
    Pieribone, Vincent A.
    Ballanyi, Klaus
    Cohen, Adam E.
    Campbell, Robert E.
    [J]. JOURNAL OF NEUROSCIENCE, 2016, 36 (08) : 2458 - 2472
  • [5] High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor
    Gong, Yiyang
    Huang, Cheng
    Li, Jin Zhong
    Grewe, Benjamin F.
    Zhang, Yanping
    Eismann, Stephan
    Schnitzer, Mark J.
    [J]. SCIENCE, 2015, 350 (6266) : 1361 - 1366
  • [6] Genetically encoded voltage indicators for large scale cortical imaging come of age[J] . Thomas Kn?pfel,Yasir Gallero-Salas,Chenchen Song.Current Opinion in Chemical Biology . 2015
  • [7] Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex
    Muller, Arnaud
    Joseph, Victory
    Slesinger, Paul A.
    Kleinfeld, David
    [J]. NATURE METHODS, 2014, 11 (12) : 1245 - +
  • [8] Imaging neural spiking in brain tissue using FRET-opsin protein voltage sensors
    Gong, Yiyang
    Wagner, Mark J.
    Li, Jin Zhong
    Schnitzer, Mark J.
    [J]. NATURE COMMUNICATIONS, 2014, 5
  • [9] Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes[J] . Thestrup Thomas,Litzlbauer Julia,Bartholom?us Ingo,Mues Marsilius,Russo Luigi,Dana Hod,Kovalchuk Yuri,Liang Yajie,Kalamakis Georgios,Laukat Yvonne,Becker Stefan,Witte Gregor,Geiger Anselm,Allen Taylor,Rome Lawrence C,Chen Tsai-Wen,Kim Douglas S,Garaschuk Olga,Griesinger Christian,Griesbeck Oliver.Nature methods . 2014 (2)
  • [10] Improved detection of electrical activity with a voltage probe based on a voltage-sensing phosphatase
    Tsutsui, Hidekazu
    Jinno, Yuka
    Tomita, Akiko
    Niino, Yusuke
    Yamada, Yoshiyuki
    Mikoshiba, Katsuhiko
    Miyawaki, Atsushi
    Okamura, Yasushi
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 2013, 591 (18): : 4427 - 4437
1234