Viral suppression of RNA silencing

被引：0

作者：

JIANG Lin

WEI ChunHong & LI Yi * State Key Laboratory of Protein and Plant Gene Research

College of Life Sciences

Peking University

Beijing 100871

China

机构：

来源：

Science China(Life Sciences) | 2012年 / 02期

关键词：

RNA silencing; viral suppressor of RNA silencing; mechanisms;

D O I：

暂无

中图分类号：

Q78 [基因工程（遗传工程）];

学科分类号：

071007 ; 0836 ; 090102 ;

摘要：

Gene silencing (RNA silencing) plays a fundamental role in antiviral defense in plants, fungi and invertebrates. Viruses encode proteins that suppress gene silencing to counter host defense. Viral suppressors of RNA silencing (VSRs) have been identified from almost all plant virus genera and some viruses of insects and mammals. Recent studies have revealed that VSRs counter host defense and interfere with host gene regulation by interacting with RNA or important components of the RNA silencing pathway. Here, we review the current understanding of the complex mechanisms of VSRs that have been revealed by recent studies.

引用

页码：109 / 118

页数：10

共 28 条

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