Design,synthesis and in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antitubercular and antimalarial agents

被引：2
|
作者：
Tarunkumar Naniibhai Akhaia [1 ]
Jignesh Privakant Raval [1 ]
机构：
[1] Department of Pharmaceutical Chemistry,Ashok & Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences(ARIBAS),New Vallabh Vidyanagar 388121,India
来源：
ChineseChemicalLetters | 2012年 / 23卷 / 07期
关键词：
Tetrahydropyrimidines-isatin hybrid; Biginelli reaction; In vitro antitubercular; Antimalarial activity;
D O I：
暂无
中图分类号：
O621.2 [有机化合物性质];
学科分类号：
070303 ; 081704 ;
摘要：
A series of 5-substituted-3-[{5-(6-methyl-2-oxo/thioxo-4-phenyl-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-oxadiazol-2-yl}-imino] -1,3-dihydro-2H-indol-2-one were synthesized,characterized and screened for their anti-tubercular and antimalarial activity.
引用
收藏
页码：785 / 788
页数：4
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