Severe cerebral abscess associated with pulmonary arteriovenous fistula: case report and literature review

Background: A rare case of cerebral abscess concurrent with pulmonary arteriovenous fistula(PAVF),hyperhemoglobinemia, and hypoxemia was reported.Case presentation: A 37-year-old man was admitted with a headache, nausea, vomiting, fever, and numbness of the left cheek and upper limb for 10 days. Cerebral magnetic resonance imaging(MRI) shows the lesion in his right frontal lobe. Blood gas analysis indicated lower blood oxygen saturation level, and blood routine test showed hemoglobin elevation. Craniotomy for the lesion and decompressive craniotomy were performed. Brain abscess was confirmed by pathology examination. The chest computed tomography angiography(CTA) revealed a pulmonary arteriovenous fistula(PAVF) in his right lower lung. After 1 month, embolization of PAVF was performed. Anoxic symptom improved after surgery. Cranioplasty was performed after 7 months.Conclusion: The author reported a rare case of cerebral abscess associated with pulmonary arteriovenous fistula.Brain abscess, hyperhemoglobinemia, and hypoxemia might be secondary to PAVF. Treatment of patients includes not only craniotomy for abscess removal but also embolization of PAVF which can prevent recurrence of brain abscess.