OX40和OX40L与自身免疫性疾病

被引：0
|
作者：
刘建 [1 ,2 ]
杨南萍 [1 ]
机构：
[1] 四川大学华西医院
[2] 四川省人民医院风湿免疫科
来源：
现代预防医学 | 2013年 / 40卷 / 05期
关键词：
OX40; OX40L; 自身免疫性疾病; 肿瘤坏死因子超家族;
D O I：
暂无
中图分类号：
R593.2 [自身免疫性疾病、结缔组织疾病];
学科分类号：
摘要：
自身免疫性疾病多数目前病因和发病机制尚未完全阐明。免疫应答异常在其中扮演非常重要的角色。近年研究发现OX40和OX40L相互作用对抗原特异性T细胞的增殖和生存具有重要意义。本文综述了OX40和OX40L的表达和调控、OX40和OX40L相互作用的生物学功能、自身免疫病中OX40和OX40L的表达和作用。
引用
收藏
页码：956 / 959
页数：4
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