Risk of postoperative recurrence and postoperative management of Crohn's disease

被引:0
作者
Antonino Spinelli [1 ]
Matteo Sacchi [1 ]
Gionata Fiorino [2 ]
Silvio Danese [2 ]
Marco Montorsi [1 ]
机构
[1] Department and Chair of General Surgery,University of Milan,Istituto Clinico Humanitas IRCCS,Via Manzoni 5620089,Rozzano,Milan,Italy
[2] IBD Unit,Department of Gastroenterology,Istituto Clinico Humanitas IRCCS,Via Manzoni 5620089,Rozzano,Milan,Italy
关键词
Crohn’s disease; Recurrence; Postoperative treatment; Surgery; Surveillance;
D O I
暂无
中图分类号
R574 [肠疾病];
学科分类号
1002 ; 100201 ;
摘要
Crohn’s disease (CD) is a chronic inflammatory disease of the digestive tract with systemic manifestations. Etiology is unknown, even if immunological, genetic and environmental factors are involved. The majority of CD patients require surgery during their lifetime due to progressive bowel damage, but, even when all macroscopic lesions have been removed by surgery, the disease recurs in most cases. Postoperative management represents therefore a crucial mean for preventing recurrence. Several drugs and approaches have been proposed to achieve this aim. Endoscopic inspection of the ileocolic anastomosis within 1 year from surgery is widely encouraged, given that endoscopic recurrence is one of the greatest predictors for clinical recurrence. A strategy should be planned only after stratifying patients according to their individual risk of recurrence, avoiding unnecessary therapies when possible benefits are reduced, and selecting high-risk patients for more aggressive intervention.
引用
收藏
页码:3213 / 3219
页数:7
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