Caffeine catalyzed green synthesis of novel benzo[a][1,3]oxazino[6,5-c]phenazines via a one-pot multi-component sequential protocol in a basic ionic liquid

被引：1

作者：

Razieh Mohebat ^{[1
]}

Afshin YazdaniElahAbadi ^{[2
]}

机构：

[1] Young Researchers and Elite Club,Yazd Branch,Islamic Azad University,Yazd,Iran

[2] Department of Biology,Science and Art University,Yazd,Iran

来源：

ChineseChemicalLetters | 2017年 / 28卷 / 06期

关键词：

Multi-component reactions(MCRs); Green chemistry; Ionic liquid; Caffeine; Oxazine; Phenazine;

D O I：

暂无

中图分类号：

O626 [杂环化合物];

学科分类号：

070303 ; 081704 ;

摘要：

Caffeine was applied as a green and natural catalyst for the one-pot,four-component sequential condensation between 2-hydroxy-1,4-naphthoquinone,aromatic 1,2-diamines,ammonium thiocyanate and acid chlorides in the presence of a basic ionic liquid(l-butyl-3-methylimidazolium hydroxide) to afford the corresponding benzo[a][1,3]oxazino[6,5-c]phenazine derivatives.In this one-pot transformation,five bonds and two new rings are efficiently formed.This protocol has the advantages of operational simplicity,high yields,easy workup,avoidance of hazardous or toxic catalysts and organic solvents and high chemo-and regioselectivities.

引用

页码：1340 / 1344

页数：5

共 11 条

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