Doping inorganic ions to regulate bioactivity of Ca–P coating on bioabsorbable high purity magnesium

被引：0

作者：

Hongliu Wu ^{[1
]}

Ruopeng Zhang ^{[1
]}

Xiao Li ^{[1
]}

Jiahua Ni ^{[1
]}

Changli Zhao ^{[1
]}

Yang Song ^{[2
]}

Jiawei Wang ^{[1
]}

Shaoxiang Zhang ^{[3
]}

Yufeng Zheng ^{[4
]}

Xiaonong Zhang ^{[1
,3
]}

机构：

[1] State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University

[2] Department of Mechanical Engineering, The University of Hong Kong

[3] Suzhou Origin Medical Technology Co. Ltd. 4. State Key Laboratory for Turbulence and Complex System,Department of Materials Science and Engineering,College of Engineering,Peking University

来源：

Progress in Natural Science:Materials International | 2014年 / 24卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Calcium phosphate coating; Adjustable bioactivity; Magnesium; Biomimetic deposition; In vitro;

D O I：

暂无

中图分类号：

R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Performance of biomaterials was strongly affected by their surface properties and could be designed artificially to meet specific biomedical requirements. In this study, F(F), Si O2 4(Si), or HCO 3(C)-doped Ca–P coatings were fabricated by biomimetic deposition on the surface of biodegradable high-purity magnesium(HP Mg). The crystalline phases, morphologies and compositions of Ca–P coatings had been characterized by X-ray diffraction(XRD), scanning electron microscopy(SEM) and energy-dispersive spectroscopy(EDS). The biomineralization and corrosion resistance of doped Ca–P coatings had also been investigated. The results showed that the Ca–P coating with or without doped elements mainly contained the plate-like dicalcium phosphate dehydrate(DCPD) phase. The doped F, Si, or C changed the surface morphology of Ca–P coatings after mineralization. Doped F enhanced the mineralization of Ca–P coating, and doped Si retarded the mineralization of Ca–P coating.However, H2 evolution of HP Mg discs with different Ca–P coatings was close to 0.4–0.7 ml/cm2 after two-week immersion. That meant that the corrosion resistance of the Ca–P coatings with different or without doped elements did not change significantly.

引用

页码：479 / 485

页数：7

共 11 条

[11] Coralline hydroxyapatite: A bone graft alternative in foot and ankle surgery[J] . Fred Rahimi,Brian T. Maurer,Matthew G. Enzweiler.The Journal of Foot and Ankle Surgery . 1997 (3)

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