Synthesis of 3,5-diarylisoxazoles under solvent-free conditions using iodobenzene diacetate

被引:0
作者
Kondapalli Venkata Gowri Chandra Sekhar [1 ]
Thripuraribhatla Venkata Naga Varuna Tara Sasank [2 ]
Hunsur Nagendra Nagesh [1 ]
Narva Suresh [1 ]
Kalaga Mahalakshmi Naidu [1 ]
Amaroju Suresh [1 ]
机构
[1] Department of Chemistry,Birla Institute of Technology and Science-Pilani,Hyderabad Campus
[2] Department of Pharmacy,Birla Institute of Technology and Science
关键词
Isoxazoles; Chalcones; Solid-state synthesis; Iodobenzene diacetate;
D O I
暂无
中图分类号
TQ242 [芳香族烃卤素衍生物];
学科分类号
0817 ;
摘要
A simple and effcient method has been developed for conversion of chalcone oximes to 3,5-diaryl isoxazoles in excellent yields under solvent-free conditions.The synthesized compounds were characterized by infrared spectroscopy,1H NMR,13C NMR and HRMS.
引用
收藏
页码:1045 / 1048
页数:4
相关论文
共 10 条
[1]  
Synthesis and antitumor activity of 2,5-bis(3′-indolyl)-furans and 3,5-bis(3′-indolyl)-isoxazoles, nortopsentin analogues[J] . Patrizia Diana,Anna Carbone,Paola Barraja,Gerhard Kelter,Heinz-Herbert Fiebig,Girolamo Cirrincione.Bioorganic & Medicinal Chemistry . 2010 (12)
[2]  
A highly efficient, green, rapid, and chemoselective oxidation of sulfides using hydrogen peroxide and boric acid as the catalyst under solvent-free conditions[J] . Amin Rostami,Jamal Akradi.Tetrahedron Letters . 2010 (27)
[3]  
Solid phase synthesis of a molecular library of pyrimidines, pyrazoles, and isoxazoles with biological potential[J] . Giovanni Pellegrino,Francesco Leonetti,Angelo Carotti,Orazio Nicolotti,Leonardo Pisani,Angela Stefanachi,Marco Catto.Tetrahedron Letters . 2010 (13)
[4]  
Hypervalent iodine(III) mediated synthesis of novel unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles as antibacterial and antifungal agents[J] . Om Prakash,Manoj Kumar,Rajesh Kumar,Chetan Sharma,K.R. Aneja.European Journal of Medicinal Chemistry . 2010 (9)
[5]  
Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents[J] . Atul Kumar,Ram Awatar Maurya,Siddharth Sharma,Pervez Ahmad,A.B. Singh,A.K. Tamrakar,Arvind K. Srivastava.Bioorganic & Medicinal Chemistry . 2009 (14)
[6]  
Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives[J] . A. Padmaja,T. Payani,G. Dinneswara Reddy,V. Padmavathi.European Journal of Medicinal Chemistry . 2009 (11)
[7]  
Convenient Synthesis of 3,5‐Disubstituted Isoxazoles[J] . Reshma F. Kurangi,Rima Kawthankar,Sulfala Sawal,Vidya G. Desai,Santosh G. Tilve.Synthetic Communications . 2007 (4)
[8]  
Iodobenzene Diacetate Mediated Solid‐State Synthesis of Heterocyclyl‐1,3,4‐oxadiazoles[J] . V. S. Rao,K. V. G. Chandra Sekhar.Synthetic Communications . 2004 (12)
[9]  
A Novel and Convenient Method for the Synthesis of 3, 5-Diarylisoxazoles[J] . Vidya G. Desai,Santosh G. Tilve.Synthetic Communications . 1999 (17)
[10]  
A Convenient Preparation of 3,5-Diarylisoxazoles[J] . Xudong Wei,Jing Fang,Yuefei Hu,Hongwen Hu.Synthesis . 1992 (12)