AIM:To review and summerize the current literatueregarding M2A wireless capsule endoscopy.METHODS:Peer reviewed publications regarding the useof capsule endoscopy as well as our personal experiencewere reviewed.RESULTS:Review of the literature dearly showed that capsuleendoscopy was superior to enteroscopy,small bowel followthrough and computerized tomography in patients withobscure gastrointestinal bleeding,iron deficiency anemia,or suspected Crohn’s disease.It was very sensitive for thediagnosis of small bowel tumors and for survailance of smallbowel pathology in patients with Gardner syndrome orfamilial adenomatous polyposis syndrome.Its role in celiacdisease and in patients with known Crohn’s disease wascurrently being investigated.CONCLUSION:Capsule video endoscopy is a superior andmore sensitive diagnostic tool than barium follow through,enteroscopy and entero-CT in establishing the diagnosis ofmany small bowel pathologies.