Synthetic studies towards daphniyunnine B: Construction of AC bicyclic skeleton with two vicinal all carbon quaternary stereocenters

被引：1
|
作者：
Haiyu Sun [1 ]
Guangmiao Wu [1 ]
Xingang Xie [1 ]
机构：
[1] State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University
来源：
ChineseChemicalLetters | 2019年 / 30卷 / 08期
基金：
中国国家自然科学基金;
关键词：
Daphniyunnine B; Vicinal quaternary stereocenters; Claisen rearrangement; Intramolecular iodo-amidation reaction;
D O I：
暂无
中图分类号：
O629.3 [生物碱];
学科分类号：
070303 ; 081704 ;
摘要：
The AC bicyclic skeleton of daphniyunnine B with the required 3 stereocenters(C4, C5 and C8) was accomplished in a concise route which featured two Claisen-type rearrangement reactions to construct the required vicinal all carbon quaternary stereocenters(C5 and C8) and an intramolecular iodocyclization reaction to assemble the cis-confused bicyclic lactam.
引用
收藏
页码：1538 / 1540
页数：3
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