<正> This paper introduces a heterogeneous distributed database system called LSZ system, where LSZ isan abbreviation of Li Shizhen, an ancient Chinese medical scientist. LSZ system adopts cluster asdistributed database node (or site). Each cluster consists of one or several microcomputers and oneserver. The paper describes its basic architecture and the prototype implementation, which includes queryprocessing and optimization, transaction manager and data language translation. The system provides auniform retrieve and update user interface through global relational data language GRDL.