First total synthesis of ocimarin

被引:0
作者
Jin Hui YangaYun Feng LiaCong Bin JiaShi Zhi JiangaWan Yi Liuab a Key Laboratory of Energy Sources EngineeringNingxia UniversityYinchuan China b School of Chemistry and Chemical EngineeringNingxia UniversityYinchuan China [750021 ,750021 ]
机构
关键词
Coumarins; Ocimarin; CeCl3·7H2O; Total synthesis;
D O I
暂无
中图分类号
O621.2 [有机化合物性质];
学科分类号
070303 ; 081704 ;
摘要
<正>A facile approach for the first synthesis of ocimarin,naturally occurring coumarins,was developed by employing a cerium(Ⅲ) chloride heptahydrate-catalyzed Pechmann condensation of phenols andβ-keto esters in a solvent-free system as key step,by which ocimarin was achieved by three steps starting from acetylacetic ether and resorcinol with total yield 23.2%.All structures of new compounds were confirmed by IR,1H NMR and MS.
引用
收藏
页码:1165 / 1166
页数:2
相关论文
共 5 条
[1]  
Estevze-Braun A,Gonzalez AG.Coumarins. Natural Products Reports . 1997
[2]  
Gupta,P,Yadav,D.K.,Maurya,K.B.,Palit,G.,Maurya,R. Journal of Natural Products . 2007
[3]  
R.D.H.Murray. Fortschr.Chem.Org.Naturst . 1991
[4]  
K.R.Kirtikar,B.D.Basu.Indian Medicinal Plants. . 1933
[5]  
J.H.Yang,C.B.Ji,Y.M.Zhao. Chinese Journal of Organic Chemistry . 2008