First total synthesis of isoquinolinone alkaloid marinamide and its methyl ester

被引:0
作者
Cheng-Liang Feng
Shu-Guang Zhang
Jun-Qing Chen
Jin Cai
Min Ji
机构
[1] InstituteofPharmaceuticalEngineering,SchoolofChemistryandChemicalEngineering,SoutheastUniversity
关键词
Marinamide; Methyl ester of marinamide; Isoquinolinone alkaloid; Total synthesis;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
<正>The first total synthesis of isoquinolinone alkaloid marinamide 1 and its methyl ester 2 was described. The key steps involved a regioselective Frieclel-Crafts reaction of 1-benzyl-1H-pyrrole to form the intermediate 8.
引用
收藏
页码:767 / 769
页数:3
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