First total synthesis of isoquinolinone alkaloid marinamide and its methyl ester

被引：0
作者：
Cheng-Liang Feng [1 ]
Shu-Guang Zhang [1 ]
Jun-Qing Chen [1 ]
Jin Cai [1 ]
Min Ji [1 ]
机构：
[1] Institute of Pharmaceutical Engineering,School of Chemistry and Chemical Engineering,Southeast University
来源：
Chinese Chemical Letters | 2013年 / 24卷 / 08期
关键词：
Marinamide; Methyl ester of marinamide; Isoquinolinone alkaloid; Total synthesis;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The first total synthesis of isoquinolinone alkaloid marinamide 1 and its methyl ester 2 was described. The key steps involved a regioselective Frieclel-Crafts reaction of 1-benzyl-1H-pyrrole to form the intermediate 8.
引用
收藏
页码：767 / 769
页数：3
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