Breast cancer and protein biomarkers

被引：1

作者：

Lay-Harn Gam ^{[1
]}

机构：

[1] School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia

来源：

World Journal of Experimental Medicine | 2012年 / 05期

关键词：

Breast cancer; Protein; Biomarkers; Proteomics;

D O I：

暂无

中图分类号：

R737.9 [乳腺肿瘤];

学科分类号：

100214 ;

摘要：

Breast cancer is a healthcare concern of women worldwide.Despite procedures being available for diagnosis,prognosis and treatment of breast cancer,researchers are working intensively on the disease in order to improve the life quality of breast cancer patients.At present,there is no single treatment known to bring a definite cure for breast cancer.One of the possible solutions for combating breast cancer is through identification of reliable protein biomarkers that can be effectively used for early detection,prognosis and treatments of the cancer.Therefore,the task of identification of biomarkers for breast cancer has become the focus of many researchers worldwide.

引用

页码：86 / 91

页数：6

共 18 条

[1] Comparative Proteome Analysis of Breast Cancer and Adjacent Normal Breast Tissues in Human [J].

ShiShan Deng TianYong Xing HongYing Zhou RuoHong Xiong YouGuang Lu Bin Wen Shang Qing Liu and HuiJun Yang Department of Anatomy West China School of Preclinical and Forensic Medicine Sichuan University Chengdu ChinaAliated Hospital of North Sichuan Medical College Nanchong China Department of Pathology Preclinical Medicine School North Sichuan Medical College Nanchong China .

Genomics Proteomics & Bioinformatics, 2006, (03) :165-172

[2]

Pilot and feasibility study: comparative proteomic analysis by 2-DE MALDI TOF/TOF MS reveals 14-3-3 proteins as putative biomarkers of response to neoadjuvant chemotherapy in ER-positive breast cancer[J] . Victoria C. Hodgkinson,Vijay Agarwal,Dalia ELFadl,John N. Fox,Penelope L. McManus,Tapan K. Mahapatra,Peter J. Kneeshaw,Philip J. Drew,Michael J. Lind,Lynn Cawkwell.Journal of Proteomics . 2012 (9)

[3]

Proteomic identification of predictive biomarkers of resistance to neoadjuvant chemotherapy in luminal breast cancer: A possible role for 14-3-3 theta/tau and tBID?[J] . Victoria C. Hodgkinson,Dalia ELFadl,Vijay Agarwal,Veerabhadram Garimella,Charlotte Russell,Ervine D. Long,John N. Fox,Penelope L. McManus,Tapan K. Mahapatra,Peter J. Kneeshaw,Philip J. Drew,Michael J. Lind,Lynn Cawkwell.Journal of Proteomics . 2011 (4)

[4]

Hallmarks of Cancer: The Next Generation[J] . Douglas Hanahan,Robert A. Weinberg.Cell . 2011 (5)

[5] The PCA and LDA analysis on the differential expression of proteins in breast cancer [J].

Liang, Seng ;

Singh, Manjit ;

Dharmaraj, Saravanan ;

Gam, Lay-Harn .

DISEASE MARKERS, 2010, 29 (05) :231-242

[6] Evaluation of changes in serum protein profiles during neoadjuvant chemotherapy in HER2-positive breast cancer using an LC-MALDI-TOF/MS procedure [J].

Mazouni, Chafika ;

Baggerly, Keith ;

Hawke, David ;

Tsavachidis, Spyros ;

Andre, Fabrice ;

Buzdar, Aman U. ;

Martin, Pierre-Marie ;

Kobayashi, Ryuji ;

Pusztai, Lajos .

PROTEOMICS, 2010, 10 (19) :3525-3532

[7] Over-expression of ERp29 attenuates doxorubicin-induced cell apoptosis through up-regulation of Hsp27 in breast cancer cells [J].

Zhang, Daohai ;

Putti, Thomas C. .

EXPERIMENTAL CELL RESEARCH, 2010, 316 (20) :3522-3531

[8]

The differential expression of aqueous soluble proteins in breast normal and cancerous tissues in relation to ethnicity of the patients;Chinese, Malay and Indian[J] . Seng Liang,Manjit Singh,Lay-Harn Gam.Disease Markers . 2010 (3)

[9]

Changes in protein expression after neoadjuvant use of aromatase inhibitors in primary breast cancer: a proteomic approach to search for potential biomarkers to predict response or resistance[J] . Christopher CP Yiu,Hironobu Sasano,Katsuhiko Ono,Louis WC Chow.Expert Opinion on Investigational Drugs . 2010 (S1)

[10]

Biomarkers for early detection of breast cancer: What, when, and where?[J] . Victor V. Levenson.BBA - General Subjects . 2007 (6)

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